Protein: ANFY1
Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)

Gene: ANFY1, ANKFY1
Organism: Homo sapiens
Interactions: 208
UniProt ID: Q9P2R3

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005765 - lysosomal membrane
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

592550

RAB5A
Ras-related protein Rab-5A

3

3

Small-scale

0.876

High

1347405

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

3

12

High-throughput

0.871

High

167028

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

2

13

High-throughput

0.793

High

1042728

CUL3
Cullin-3

2

7

Small-scale

0.789

High

1189523

ZFY16
Zinc finger FYVE domain-containing protein 16

2

7

Small-scale

0.754

High

120691

RHOD
Rho-related GTP-binding protein RhoD

1

10

Small-scale

0.740

High

1138668

ARHGG
Rho guanine nucleotide exchange factor 16

2

10

High-throughput

0.737

High

1335366

RHOF
Rho-related GTP-binding protein RhoF

1

10

Small-scale

0.713

High

225163

MYPT2
Protein phosphatase 1 regulatory subunit 12B

1

19

High-throughput

0.691

High

851719

NEK4
Serine/threonine-protein kinase Nek4

1

6

High-throughput

0.691

High

1232340

MILK1
MICAL-like protein 1

1

12

Small-scale

0.691

High

1331788

EHD1
EH domain-containing protein 1

3

12

Small-scale

0.684

High

1080426

EZH2
Histone-lysine N-methyltransferase EZH2

1

2

High-throughput

0.665

High

1153194

SPOPL
Speckle-type POZ protein-like

1

0

High-throughput

0.656

High

833830

CLK1
Dual specificity protein kinase CLK1

1

3

High-throughput

0.647

High

943002

SRPK2
SRSF protein kinase 2

1

6

High-throughput

0.647

High

279899

TRIO
Triple functional domain protein

1

20

High-throughput

0.618

High

313574

ZFYV9
Zinc finger FYVE domain-containing protein 9

1

9

High-throughput

0.618

High

325926

LATS1
Serine/threonine-protein kinase LATS1

1

2

High-throughput

0.618

High

339073

EGFR
Epidermal growth factor receptor

1

9

Small-scale

0.618

High

508244

FGFR1
Fibroblast growth factor receptor 1

1

13

High-throughput

0.618

High

548761

VAV
Proto-oncogene vav

1

5

High-throughput

0.618

High

851364

NEK2
Serine/threonine-protein kinase Nek2

1

5

Small-scale

0.618

High

957821

RHG04
Rho GTPase-activating protein 4

1

9

High-throughput

0.618

High

1023132

STK4
Serine/threonine-protein kinase 4

1

8

High-throughput

0.618

High

1027449

STK3
Serine/threonine-protein kinase 3

1

8

High-throughput

0.618

High

1043272

CUL4A
Cullin-4A

1

7

High-throughput

0.618

High

1050495

DOCK1
Dedicator of cytokinesis protein 1

1

7

High-throughput

0.618

High

1067481

EEA1
Early endosome antigen 1

1

9

High-throughput

0.618

High

1082041

PKN2
Serine/threonine-protein kinase N2

1

1

High-throughput

0.618

High

1110116

AR13B
ADP-ribosylation factor-like protein 13B

1

4

High-throughput

0.618

High

1301667

KS6C1
Ribosomal protein S6 kinase delta-1

1

2

High-throughput

0.618

High

1302778

RUFY1
RUN and FYVE domain-containing protein 1

1

10

High-throughput

0.618

High

1328761

RBNS5
Rabenosyn-5

1

6

High-throughput

0.618

High

1349374

PD1L1
Programmed cell death 1 ligand 1

1

2

Small-scale

0.618

High

1350525

KDIS
Kinase D-interacting substrate of 220 kDa

1

14

High-throughput

0.618

High

382549

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

0

High-throughput

0.586

High

714594

GRK5
G protein-coupled receptor kinase 5

1

0

High-throughput

0.586

High

960126

CDK3
Cyclin-dependent kinase 3

1

0

High-throughput

0.586

High

228949

PRKN
E3 ubiquitin-protein ligase parkin

2

4

High-throughput

0.584

High

1326191

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

2

15

High-throughput

0.584

High

1330355

PTN23
Tyrosine-protein phosphatase non-receptor type 23

2

4

Small-scale

0.584

High

1130682

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.575

High

164698

MAST4
Microtubule-associated serine/threonine-protein kinase 4

1

1

High-throughput

0.553

High

324897

M4K4
Mitogen-activated protein kinase kinase kinase kinase 4

1

11

High-throughput

0.553

High

665348

EPHA2
Ephrin type-A receptor 2

1

8

High-throughput

0.553

High

1172084

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.553

High

1237559

ANR44
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B

1

18

High-throughput

0.553

High

128926

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

1

High-throughput

0.536

High

306344

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

15

High-throughput

0.536

High

891348

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

15

High-throughput

0.536

High

973649

CREB5
Cyclic AMP-responsive element-binding protein 5

1

2

High-throughput

0.536

High

996941

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.536

High

1244186

UBP32
Ubiquitin carboxyl-terminal hydrolase 32

1

7

High-throughput

0.536

High

1300505

VPS35
Vacuolar protein sorting-associated protein 35

1

1

Small-scale

0.536

High

1169917

PKHG7
Pleckstrin homology domain-containing family G member 7

2

14

High-throughput

0.521

High

1205903

MF2L2
Probable guanine nucleotide exchange factor MCF2L2

2

12

High-throughput

0.521

High

271662

ERAL1
GTPase Era, mitochondrial

1

0

High-throughput

0.513

High

1103416

AP5B1
AP-5 complex subunit beta-1

1

0

High-throughput

0.513

High

1271371

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1310988

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.513

High

1349321

EHD3
EH domain-containing protein 3

1

12

Small-scale

0.506

High

476499

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.501

High

1326827

PRD14
PR domain zinc finger protein 14

1

2

Small-scale

0.500

High

1314410

DDA1
DET1- and DDB1-associated protein 1

1

1

High-throughput

0.489

High

1349949

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

9

High-throughput

0.489

High

203471

MTG8R
Protein CBFA2T2

1

0

Small-scale

0.479

High

50623

PKHG3
Pleckstrin homology domain-containing family G member 3

1

7

High-throughput

0.479

High

59705

WDR91
WD repeat-containing protein 91

1

7

High-throughput

0.479

High

64838

TBKB1
TANK-binding kinase 1-binding protein 1

1

6

High-throughput

0.479

High

150760

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

9

High-throughput

0.479

High

151233

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

7

High-throughput

0.479

High

157145

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.479

High

165878

KDM6B
Lysine-specific demethylase 6B

1

10

Small-scale

0.479

High

178834

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

203256

SYNJ1
Synaptojanin-1

1

1

High-throughput

0.479

High

211682

ACTN4
Alpha-actinin-4

1

9

High-throughput

0.479

High

213040

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

232561

KDM1A
Lysine-specific histone demethylase 1A

1

4

High-throughput

0.479

High

235004

SNX3
Sorting nexin-3

1

6

High-throughput

0.479

High

237630

DIAP1
Protein diaphanous homolog 1

1

2

High-throughput

0.479

High

240450

SNX2
Sorting nexin-2

1

6

High-throughput

0.479

High

242146

PAGE4
P antigen family member 4

1

3

High-throughput

0.479

High

261734

VAMP4
Vesicle-associated membrane protein 4

1

2

High-throughput

0.479

High

298852

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

302613

CE152
Centrosomal protein of 152 kDa

1

7

High-throughput

0.479

High

317370

PCNT
Pericentrin

1

14

High-throughput

0.479

High

323246

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

348124

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

377764

GCR
Glucocorticoid receptor

1

6

High-throughput

0.479

High

385648

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

430364

PROF1
Profilin-1

1

3

High-throughput

0.479

High

553948

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

610519

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.479

High

652486

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

669036

PML
Protein PML

1

7

High-throughput

0.479

High

685073

STIP1
Stress-induced-phosphoprotein 1

1

1

High-throughput

0.479

High

855752

KIF11
Kinesin-like protein KIF11

1

4

High-throughput

0.479

High

909264

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

926262

VAMP2
Vesicle-associated membrane protein 2

1

3

High-throughput

0.479

High

971074

DSC2
Desmocollin-2

1

2

High-throughput

0.479

High

975083

CAV1
Caveolin-1

1

2

High-throughput

0.479

High

980720

TLE2
Transducin-like enhancer protein 2

1

7

High-throughput

0.479

High

993083

RHG01
Rho GTPase-activating protein 1

1

6

High-throughput

0.479

High

1034637

GOGA4
Golgin subfamily A member 4

1

9

High-throughput

0.479

High

1038769

HDAC1
Histone deacetylase 1

1

4

High-throughput

0.479

High

1048458

LRP8
Low-density lipoprotein receptor-related protein 8

1

2

High-throughput

0.479

High

1048679

DSG2
Desmoglein-2

1

2

High-throughput

0.479

High

1052502

FLOT2
Flotillin-2

1

2

High-throughput

0.479

High

1079461

VAMP3
Vesicle-associated membrane protein 3

1

2

High-throughput

0.479

High

1084223

OCLN
Occludin

1

2

High-throughput

0.479

High

1086008

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1129145

CYTSB
Cytospin-B

1

9

High-throughput

0.479

High

1133713

RHG21
Rho GTPase-activating protein 21

1

9

High-throughput

0.479

High

1148836

VIR
Protein virilizer homolog

1

3

High-throughput

0.479

High

1158656

C2D1A
Coiled-coil and C2 domain-containing protein 1A

1

6

High-throughput

0.479

High

1168430

LMTK1
Serine/threonine-protein kinase LMTK1

1

20

High-throughput

0.479

High

1187835

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

8

High-throughput

0.479

High

1199705

ZN598
E3 ubiquitin-protein ligase ZNF598

1

4

High-throughput

0.479

High

1205388

STX12
Syntaxin-12

1

3

High-throughput

0.479

High

1205860

CPNE8
Copine-8

1

2

High-throughput

0.479

High

1218768

GCC2
GRIP and coiled-coil domain-containing protein 2

1

11

High-throughput

0.479

High

1237507

CGAS
Cyclic GMP-AMP synthase

1

1

High-throughput

0.479

High

1238273

JMY
Junction-mediating and -regulatory protein

1

2

High-throughput

0.479

High

1243522

DP13B
DCC-interacting protein 13-beta

1

4

High-throughput

0.479

High

1254011

ALMS1
Centrosome-associated protein ALMS1

1

12

High-throughput

0.479

High

1270965

KAT6A
Histone acetyltransferase KAT6A

1

6

High-throughput

0.479

High

1273665

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

7

High-throughput

0.479

High

1282536

MUL1
Mitochondrial ubiquitin ligase activator of NFKB 1

1

1

Small-scale

0.479

High

1285379

PF21A
PHD finger protein 21A

1

8

High-throughput

0.479

High

1296940

SNX27
Sorting nexin-27

1

9

High-throughput

0.479

High

1296999

KI16B
Kinesin-like protein KIF16B

1

3

High-throughput

0.479

High

1315809

MLP3C
Microtubule-associated proteins 1A/1B light chain 3C

1

15

High-throughput

0.479

High

1318953

TB182
182 kDa tankyrase-1-binding protein

1

16

High-throughput

0.479

High

1319375

RHG39
Rho GTPase-activating protein 39

1

8

High-throughput

0.479

High

1327797

RGAP1
Rac GTPase-activating protein 1

1

9

High-throughput

0.479

High

1328056

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

15

High-throughput

0.479

High

1329440

S38A1
Sodium-coupled neutral amino acid symporter 1

1

1

High-throughput

0.479

High

1333073

AT133
Polyamine-transporting ATPase 13A3

1

1

High-throughput

0.479

High

1334943

XPO5
Exportin-5

1

5

High-throughput

0.479

High

1335216

RC3H2
Roquin-2

1

14

High-throughput

0.479

High

1336102

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

5

High-throughput

0.479

High

1343354

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

High-throughput

0.479

High

1345170

VPS45
Vacuolar protein sorting-associated protein 45

1

1

High-throughput

0.479

High

1345423

KIF15
Kinesin-like protein KIF15

1

3

High-throughput

0.479

High

1349329

ARHGC
Rho guanine nucleotide exchange factor 12

1

7

High-throughput

0.479

High

1350006

RHG23
Rho GTPase-activating protein 23

1

11

High-throughput

0.479

High

1350105

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

2

High-throughput

0.479

High

1350520

ZRAN1
Ubiquitin thioesterase ZRANB1

1

9

High-throughput

0.479

High

1350522

LCAP
Leucyl-cystinyl aminopeptidase

1

2

High-throughput

0.479

High

1350523

CDC23
Cell division cycle protein 23 homolog

1

2

High-throughput

0.479

High

1350524

RCOR1
REST corepressor 1

1

3

High-throughput

0.479

High

1350526

SNX6
Sorting nexin-6

1

6

High-throughput

0.479

High

1350527

STX8
Syntaxin-8

1

2

High-throughput

0.479

High

1350529

FARP1
FERM, ARHGEF and pleckstrin domain-containing protein 1

1

10

High-throughput

0.479

High

1350530

SNX9
Sorting nexin-9

1

6

High-throughput

0.479

High

1350531

SNX5
Sorting nexin-5

1

6

High-throughput

0.479

High

1129209

CD158
Coiled-coil domain-containing protein 158

1

9

High-throughput

0.470

High

48839

BLT3B
Bridge-like lipid transfer protein family member 3B

1

0

High-throughput

0.458

High

118088

SNP23
Synaptosomal-associated protein 23

1

0

High-throughput

0.458

High

168459

SCAM1
Secretory carrier-associated membrane protein 1

1

0

High-throughput

0.458

High

180952

YKT6
Synaptobrevin homolog YKT6

1

0

High-throughput

0.458

High

264750

VP26A
Vacuolar protein sorting-associated protein 26A

1

0

Small-scale

0.458

High

280311

CBPD
Carboxypeptidase D

1

0

High-throughput

0.458

High

321306

TBCD8
TBC1 domain family member 8

1

0

High-throughput

0.458

High

364464

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.458

High

437498

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

514922

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

High-throughput

0.458

High

792223

ECE1
Endothelin-converting enzyme 1

1

0

High-throughput

0.458

High

873992

S12A2
Solute carrier family 12 member 2

1

0

High-throughput

0.458

High

896244

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.458

High

1032661

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.458

High

1062205

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1062436

PAF15
PCNA-associated factor

1

0

Small-scale

0.458

High

1073317

DLGP5
Disks large-associated protein 5

1

0

High-throughput

0.458

High

1144531

AP1AR
AP-1 complex-associated regulatory protein

1

0

High-throughput

0.458

High

1145590

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.458

High

1232474

VPS8
Vacuolar protein sorting-associated protein 8 homolog

1

0

High-throughput

0.458

High

1244801

RAI3
Retinoic acid-induced protein 3

1

0

High-throughput

0.458

High

1304498

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

1307030

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1318594

SPY4
Protein sprouty homolog 4

1

0

High-throughput

0.458

High

1329471

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

0

High-throughput

0.458

High

1350086

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.458

High

1350521

ABC3B
DNA dC->dU-editing enzyme APOBEC-3B

1

0

Small-scale

0.458

High

1350528

MEMO1
Protein MEMO1

1

0

High-throughput

0.458

High

497715

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.445

High

1269820

ESR2
Estrogen receptor beta

1

6

High-throughput

0.445

High

721667

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1015795

KIF1A
Kinesin-like protein KIF1A

1

4

High-throughput

0.437

High

1081765

AINX
Alpha-internexin

1

12

High-throughput

0.437

High

1133666

CC183
Coiled-coil domain-containing protein 183

1

1

High-throughput

0.437

High

1136960

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

4

High-throughput

0.437

High

1169990

RHG36
Rho GTPase-activating protein 36

1

9

High-throughput

0.437

High

1233861

ARG39
Rho guanine nucleotide exchange factor 39

1

11

High-throughput

0.437

High

1255141

DLG5
Disks large homolog 5

1

6

High-throughput

0.437

High

1256646

SNX29
Sorting nexin-29

1

4

High-throughput

0.437

High

1260791

DEP1B
DEP domain-containing protein 1B

1

7

High-throughput

0.437

High

1300315

S38A2
Sodium-coupled neutral amino acid symporter 2

1

1

High-throughput

0.437

High

1331512

PKHA4
Pleckstrin homology domain-containing family A member 4

1

13

High-throughput

0.437

High

1336343

K1549
UPF0606 protein KIAA1549

1

6

High-throughput

0.437

High

1350311

SI1L2
Signal-induced proliferation-associated 1-like protein 2

1

3

High-throughput

0.437

High

1238924

SAXO5
Stabilizer of axonemal microtubules 5

2

0

High-throughput

0.328

High

259482

NIPS2
Protein NipSnap homolog 2

1

0

High-throughput

0.279

Low

1139903

USPL1
SUMO-specific isopeptidase USPL1

1

0

High-throughput

0.269

Low

783498

S19A1
Reduced folate transporter

1

0

High-throughput

0.249

Low

1238852

TTC29
Tetratricopeptide repeat protein 29

1

0

High-throughput

0.249

Low

1350253

F135A
Protein FAM135A

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024