HitPredict

Interactor 1: UBP39 (Q53GS9)
Ubiquitin carboxyl-terminal hydrolase 39 (EC 3.4.19.12) (SAD1 homolog) (U4/U6.U5 tri-snRNP-associated 65 kDa protein)
Gene: USP39

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	23105109
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 565 Hs			1 522
+	Hs
		1273989 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		1377879 UBP3_HUMAN (105-563): 1.97e-121: 369: 19.73		TRAF6_HUMAN (1-522): 1.12e-151: 445: 100.00
+	Hs
		1020848 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		1273839 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRAF4_HUMAN (54-500): 6.36e-91: 287: 26.11
+	Hs
		271081 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRAF2_HUMAN (40-500): 7.2e-101: 314: 25.85
+	Hs
		129585 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRAF5_HUMAN (43-500): 4.95e-87: 280: 25.23
+	Hs
		1024726 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRAF3_HUMAN (19-501): 9.91e-86: 277: 22.18
+	Hs
		1052677 UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00		TRI25_HUMAN (63-370): 4.93e-45: 169: 18.61
+	Hs
		1019313 UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00		TRI26_HUMAN (61-410): 2.85e-38: 149: 14.59
+	Hs
		1121195 UBP39_HUMAN (1-565): 2.92e-163: 478: 100.00		TRIM5_HUMAN (56-315): 8.46e-38: 147: 16.11
+	Hs
		1023747 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		271082 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		1273788 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI11_HUMAN (59-404): 1.13e-49: 179: 12.75
+	Hs
		536961 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		1223388 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI22_HUMAN (56-361): 5.96e-39: 150: 15.51
+	Hs
		1273857 UBP7_HUMAN (10-557): 4.92e-116: 371: 14.06		TRI31_HUMAN (58-334): 3.02e-35: 138: 15.00
+	Hs
		271032 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		RO52_HUMAN (64-403): 5.77e-45: 166: 14.97
+	Hs
		271027 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		271136 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		TRI50_HUMAN (60-403): 1.01e-39: 152: 14.12
+	Hs
		271142 UBP2_HUMAN (180-560): 5.95e-109: 340: 21.83		LNX2_HUMAN (58-183): 1.56e-11: 69.1: 21.88