Interactor 1: Q53XC2 (Q53XC2)
Translation initiation factor eIF2B subunit beta (eIF2B GDP-GTP exchange factor subunit beta)
Gene: EIF2B2

Interactor 2: EI2BD (Q9UI10)
Translation initiation factor eIF2B subunit delta (eIF2B GDP-GTP exchange factor subunit delta)
Gene: EIF2B4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.44 1.00 0.665

The method score is based on:

Property Details
Experiments 25416956
Identification Methods two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~IF-2B
Common GO terms GO:0003743 - translation initiation factor activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005829 - cytosol
GO:0005851 - eukaryotic translation initiation factor 2B complex
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 351
Hs

1 523
+ Hs
+ Hs
+ Sp
+ Dm
+ Sc
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Dm
+ Sc
+ Ce
+ Hv
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024