HitPredict

Interactor 1: H90B4 (Q58FF6)
Putative heat shock protein HSP 90-beta 4
Gene: HSP90AB4P

Interactor 2: AGO3 (Q9H9G7)
Protein argonaute-3 (Argonaute3) (hAgo3) (EC 3.1.26.n2) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3)
Gene: AGO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.50	0.60	0.552

Property	Details
Experiments	28514442, 33961781
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 860
+	Hs
		438537 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO3_HUMAN (1-860): 0: 1182: 100.00
+	Hs
		432271 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO3_HUMAN (1-860): 0: 1182: 100.00
+	Hs
		438615 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO1_HUMAN (9-860): 0: 1150: 84.62
+	Mm
		1174807 Q71LX8_MOUSE (1-504): 0: 673: 70.11		AGO2_MOUSE (3-860): 0: 1144: 79.56
+	Hs
		438614 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO2_HUMAN (15-860): 0: 1142: 80.73
+	Hs
		432356 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO1_HUMAN (9-860): 0: 1150: 84.62
+	Hs
		432355 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO2_HUMAN (15-860): 0: 1142: 80.73
+	Mm
		432448 HS90A_MOUSE (1-504): 0: 652: 61.81		AGO2_MOUSE (3-860): 0: 1144: 79.56
+	Hs
		438545 HS90B_HUMAN (1-504): 0: 671: 69.93		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Hs
		1123444 H90B4_HUMAN (1-505): 0: 644: 100.00		AGO2_HUMAN (15-860): 0: 1142: 80.73
+	Hs
		432278 HS90A_HUMAN (1-504): 0: 655: 62.96		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Dm
		365460 HSP83_DROME (1-504): 0: 669: 57.69		Q32KD4_DROME (1-860): 0: 1102: 70.89
+	Hs
		1123442 H90B4_HUMAN (1-505): 0: 644: 100.00		AGO4_HUMAN (3-860): 0: 1118: 80.81
+	Hs
		432159 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL1_HUMAN (9-827): 0: 769: 21.57
+	Dm
		365485 HSP83_DROME (1-504): 0: 669: 57.69		AGO2_DROME (22-820): 0: 696: 30.41
+	Hs
		432088 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL2_HUMAN (5-822): 0: 710: 21.39
+	Hs
		432003 HS90A_HUMAN (1-504): 0: 655: 62.96		PIWL4_HUMAN (11-823): 0: 677: 20.96
+	Dm
		365462 HSP83_DROME (1-504): 0: 669: 57.69		AGO3_DROME (23-827): 0: 624: 20.05
+	Dm
		365480 HSP83_DROME (1-504): 0: 669: 57.69		PIWI_DROME (21-827): 0: 614: 21.64
+	Hs
		431946 HS90A_HUMAN (1-504): 0: 655: 62.96		Q5TA56_HUMAN (1-219): 4.81e-159: 464: 100.00