HitPredict

Interactor 1: RUN3A (Q59EK9)
RUN domain-containing protein 3A (Rap2-interacting protein 8) (RPIP-8)
Gene: RUNDC3A

Interactor 2: AP2M1 (Q96CW1)
AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: AP2M1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.50	0.619

Property	Details
Experiments	16189514, 28514442, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 446 Hs			1 435
+	Hs
		1123885 RUN3A_HUMAN (1-446): 4.01e-169: 484: 100.00		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		1302752 RUFY1_HUMAN (17-401): 9.69e-84: 273: 18.75		AP1M1_HUMAN (2-434): 5.69e-170: 484: 38.85
+	Hs
		1302803 RUFY1_HUMAN (17-401): 9.69e-84: 273: 18.75		AP1M2_HUMAN (2-434): 5.35e-163: 467: 37.70
+	Hs
		1256639 SNX29_HUMAN (19-410): 5.69e-47: 174: 15.86		AP2M1_HUMAN (1-435): 1.03e-178: 507: 100.00
+	Hs
		1302793 RUFY1_HUMAN (17-401): 9.69e-84: 273: 18.75		AP3M1_HUMAN (1-434): 1.4e-123: 366: 24.66