HitPredict

Interactor 1: FILA2 (Q5D862)
Filaggrin-2 (FLG-2) (Intermediate filament-associated and psoriasis-susceptibility protein) (Ifapsoriasin)
Gene: FLG2

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	27591049
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2391 Hs			1 956
+	Hs
		358561 CO1A1_HUMAN (1843-2388): 1.97e-35: 151: 10.70		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		416518 S10A9_HUMAN (1-109): 6.76e-42: 151: 30.91		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		396807 S10A8_HUMAN (1-95): 8.99e-36: 133: 29.47		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		596325 FILA_HUMAN (85-1558): 5.36e-18: 94: 17.52		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		727320 NU214_HUMAN (180-979): 2.9e-17: 91.5: 14.63		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		436048 CO1A2_HUMAN (2134-2388): 1.29e-13: 79.4: 10.16		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1206200 HORN_HUMAN (1590-2390): 3.13e-13: 78: 17.93		CYLD_HUMAN (1-956): 0: 1872: 100.00