HitPredict

Interactor 1: FLNA (P21333)
Filamin-A (FLN-A) (Actin-binding protein 280) (ABP-280) (Alpha-filamin) (Endothelial actin-binding protein) (Filamin-1) (Non-muscle filamin)
Gene: FLNA

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	35973513, 37120454, 26134617, 17461779
Identification Methods	proximity labelling technology, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0030036 - actin cytoskeleton organization GO:0043066 - negative regulation of apoptotic process
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2647 Hs			1 1708
+	Hs
		278110 FLNB_HUMAN (28-2647): 0: 2710: 69.63		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		1125351 FLNC_HUMAN (32-2647): 0: 1436: 35.86		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		1028798 SPTB2_HUMAN (22-460): 7.69e-117: 418: 24.62		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		555706 ACTN1_HUMAN (21-459): 1.48e-117: 398: 24.18		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		224733 ACTN4_HUMAN (23-459): 3.26e-115: 392: 24.06		RICTR_HUMAN (1-1708): 0: 2775: 100.00