HitPredict

Interactor 1: RBM39 (Q14498)
RNA-binding protein 39 (CAPER alpha) (CAPERalpha) (Hepatocellular carcinoma protein 1) (RNA-binding motif protein 39) (RNA-binding region-containing protein 2) (Splicing factor HCC1)
Gene: RBM39

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	26725010, 29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0008380 - RNA splicing GO:0048024 - regulation of mRNA splicing, via spliceosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 530 Hs			1 582
+	Hs
		1194440 PUF60_HUMAN (141-513): 7.15e-66: 225: 19.41		LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00
+	Hs
		1194132 PAP1L_HUMAN (83-445): 4.15e-58: 205: 18.87		LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00
+	Hs
		431128 RBM39_HUMAN (1-530): 3.07e-101: 316: 100.00		LA_HUMAN (24-365): 5.99e-44: 163: 18.83
+	Hs
		1101955 RBM39_HUMAN (1-530): 3.07e-101: 316: 100.00		PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98
+	Hs
		550285 RBM39_HUMAN (1-530): 3.07e-101: 316: 100.00		PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29
+	Hs
		1126962 RBM39_HUMAN (1-530): 3.07e-101: 316: 100.00		LARP4_HUMAN (22-216): 3.24e-40: 157: 21.32
+	Hs
		1127138 RBM39_HUMAN (1-530): 3.07e-101: 316: 100.00		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1126956 RBM39_HUMAN (1-530): 3.07e-101: 316: 100.00		LARP1_HUMAN (29-114): 6.38e-13: 73.8: 40.23
+	Hs
		431270 PUF60_HUMAN (141-513): 7.15e-66: 225: 19.41		LA_HUMAN (24-365): 5.99e-44: 163: 18.83
+	Hs
		1126909 RBM39_HUMAN (1-530): 3.07e-101: 316: 100.00		ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50
+	Hs
		1102128 PUF60_HUMAN (141-513): 7.15e-66: 225: 19.41		PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98
+	Hs
		550508 PUF60_HUMAN (141-513): 7.15e-66: 225: 19.41		PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29
+	Hs
		1197178 PAP1L_HUMAN (83-445): 4.15e-58: 205: 18.87		PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11
+	Hs
		550311 PAP1L_HUMAN (83-445): 4.15e-58: 205: 18.87		PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29
+	At
		306156 PABP2_ARATH (251-530): 9.95e-43: 163: 17.61		LRP6B_ARATH (2-265): 6.45e-54: 194: 21.20
+	Sc
		403432 PABP_YEAST (40-429): 2.84e-51: 186: 14.11		LHP1_YEAST (7-270): 1.35e-45: 163: 22.74
+	At
		842070 PABP2_ARATH (251-530): 9.95e-43: 163: 17.61		LRP6C_ARATH (12-249): 1.54e-49: 179: 23.14
+	Hs
		1197174 PAP1L_HUMAN (83-445): 4.15e-58: 205: 18.87		PABP5_HUMAN (12-206): 3.66e-32: 129: 14.15
+	Sc
		403283 PABP_YEAST (40-429): 2.84e-51: 186: 14.11		PABP_YEAST (9-243): 4.77e-33: 135: 13.47
+	Mm
		1000307 Q80ZW7_MOUSE (155-418): 3.03e-55: 191: 20.71		ELAV1_MOUSE (92-211): 6.46e-13: 71.9: 22.50