HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: PUF60 (Q9UHX1)
Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)
Gene: PUF60

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1, RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:1990904 - ribonucleoprotein complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 582 Hs			1 559
+	Hs
		1126931 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		RBM39_HUMAN (113-555): 5.64e-70: 235: 19.78
+	Hs
		431270 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		PUF60_HUMAN (1-559): 3e-102: 321: 100.00
+	Hs
		1194132 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PAP1L_HUMAN (476-559): 8.32e-15: 79.6: 19.05
+	Hs
		550310 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP1_HUMAN (478-559): 4.3e-14: 77.3: 17.07
+	Hs
		1194374 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP3_HUMAN (478-559): 4.84e-13: 73.8: 18.29
+	Hs
		1101980 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		PABP4_HUMAN (470-550): 5.89e-11: 67.2: 12.35
+	Hs
		431128 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		RBM39_HUMAN (113-555): 5.64e-70: 235: 19.78
+	Hs
		1101955 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		RBM39_HUMAN (113-555): 5.64e-70: 235: 19.78
+	At
		306158 LRP6B_ARATH (2-265): 6.45e-54: 194: 21.20		PABP8_ARATH (470-559): 8.43e-21: 98.4: 15.56
+	At
		306156 LRP6B_ARATH (2-265): 6.45e-54: 194: 21.20		PABP2_ARATH (470-559): 6.2e-18: 89.2: 14.44
+	At
		842070 LRP6C_ARATH (12-249): 1.54e-49: 179: 23.14		PABP2_ARATH (470-559): 6.2e-18: 89.2: 14.44
+	Hs
		1102044 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		CELF1_HUMAN (98-214): 1.47e-17: 87.5: 26.50
+	Hs
		1090216 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		ELAV2_HUMAN (432-549): 2.27e-16: 82.6: 11.86
+	Hs
		1197178 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PAP1L_HUMAN (476-559): 8.32e-15: 79.6: 19.05
+	Hs
		550464 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PABP1_HUMAN (478-559): 4.3e-14: 77.3: 17.07
+	Hs
		506129 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		PAB4L_HUMAN (478-559): 4.85e-15: 78.8: 20.73
+	Hs
		550262 PABP4_HUMAN (1-208): 3.12e-41: 160: 11.98		PABP1_HUMAN (478-559): 4.3e-14: 77.3: 17.07
+	Sc
		403432 LHP1_YEAST (7-270): 1.35e-45: 163: 22.74		PABP_YEAST (440-553): 3.03e-12: 71.1: 16.67
+	Hs
		1102095 PABP3_HUMAN (1-333): 2.14e-42: 163: 10.11		PABP4_HUMAN (470-550): 5.89e-11: 67.2: 12.35
+	Hs
		431115 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		PABP4_HUMAN (470-550): 5.89e-11: 67.2: 12.35