Interactor 1: DPH1 (Q5NCQ5)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 (EC 2.5.1.108) (Diphthamide biosynthesis protein 1) (Diphtheria toxin resistance protein 1) (Ovarian cancer-associated gene 1 protein homolog) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 1)
Gene: DPH1

Interactor 2: DPH2 (Q9CR25)
2-(3-amino-3-carboxypropyl)histidine synthase subunit 2 (Diphthamide biosynthesis protein 2) (Diphtheria toxin resistance protein 2) (MmDph2) (S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase DPH2)
Gene: DPH2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15485916
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Diphthamide_syn~Diphthamide_syn
Common GO terms GO:0017183 - protein histidyl modification to diphthamide
GO:0032991 - protein-containing complex
GO:0046872 - metal ion binding
GO:0051539 - 4 iron, 4 sulfur cluster binding
GO:0090560 - 2-(3-amino-3-carboxypropyl)histidine synthase activity
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 438
Mm

1 489
+ Hs
+ Dm
+ Ce
+ Sc
+ Sp
+ Ph

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024