HitPredict

Interactor 1: MDC1 (Q14676)
Mediator of DNA damage checkpoint protein 1 (Nuclear factor with BRCT domains 1)
Gene: MDC1

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	29656893, 36526897
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FHA~PH
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 2089 Hs			1 1124
+	Hs
		799498 BRCA1_HUMAN (405-2081): 8.49e-75: 279: 8.23		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		854326 KI67_HUMAN (38-1926): 1.25e-69: 263: 9.54		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1447449 SRRM2_HUMAN (97-1940): 1.48e-24: 115: 8.27		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1253876 SRCAP_HUMAN (537-1551): 5.03e-20: 100: 10.68		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1403512 MINT_HUMAN (224-1896): 3.16e-16: 88.1: 11.94		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1370945 PRG4_HUMAN (1400-1906): 3.3e-09: 64.6: 14.51		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		799287 BRCA1_HUMAN (405-2081): 8.49e-75: 279: 8.23		RTKN2_HUMAN (724-1113): 1.09e-112: 365: 18.23
+	Hs
		1316143 TITIN_HUMAN (137-816): 5.64e-12: 74.2: 7.90		RTKN2_HUMAN (724-1113): 1.09e-112: 365: 18.23