HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: HIBCH (Q6NVY1)
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (EC 3.1.2.4) (3-hydroxyisobutyryl-coenzyme A hydrolase) (HIB-CoA hydrolase) (HIBYL-CoA-H)
Gene: HIBCH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005759 - mitochondrial matrix
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 386
+	Hs
		91652 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		E9KL44_HUMAN (5-354): 1.37e-89: 287: 19.02
+	Hs
		671462 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		ECHM_HUMAN (9-294): 3.83e-85: 262: 27.40
+	Hs
		1130196 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		Q6IBN4_HUMAN (30-290): 1.19e-72: 232: 15.91
+	Hs
		671459 LRRK1_HUMAN (771-1194): 2.3e-35: 151: 16.38		ECHM_HUMAN (9-294): 3.83e-85: 262: 27.40
+	Hs
		201233 M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83		ECHM_HUMAN (9-294): 3.83e-85: 262: 27.40