Protein: TOP2A
DNA topoisomerase 2-alpha (EC 5.6.2.2) (DNA topoisomerase II, alpha isozyme)

Gene: TOP2A
Organism: Mus musculus
Interactions: 33
UniProt ID: Q01320

Gene Ontology (top 5):
GO:0000228 - nuclear chromosome
GO:0000287 - magnesium ion binding
GO:0000712 - resolution of meiotic recombination intermediates
GO:0000775 - chromosome, centromeric region
GO:0000793 - condensed chromosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

590303

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.536

High

57766

ARI1A
AT-rich interactive domain-containing protein 1A

1

3

Small-scale

0.500

High

222671

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

3

Small-scale

0.500

High

956807

SMRC1
SWI/SNF complex subunit SMARCC1

1

2

Small-scale

0.500

High

964603

SMCA4
Transcription activator BRG1

1

11

Small-scale

0.500

High

964608

REQU
Zinc finger protein ubi-d4

1

8

Small-scale

0.500

High

964609

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

2

Small-scale

0.500

High

964610

SSXT
Protein SSXT

1

3

Small-scale

0.500

High

964613

PB1
Protein polybromo-1

1

16

Small-scale

0.500

High

964621

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

Small-scale

0.500

High

821706

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C]

1

4

Small-scale

0.479

High

862809

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

Small-scale

0.479

High

926401

MK01
Mitogen-activated protein kinase 1

1

3

Small-scale

0.479

High

964605

TET2
Methylcytosine dioxygenase TET2

1

1

Small-scale

0.479

High

964611

FACD2
Fanconi anemia group D2 protein homolog

1

3

High-throughput

0.479

High

964612

NANOG
Homeobox protein NANOG

1

1

High-throughput

0.479

High

964615

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.479

High

964616

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

8

Small-scale

0.479

High

964618

RBP2
E3 SUMO-protein ligase RanBP2

1

3

Small-scale

0.479

High

964619

CUL3
Cullin-3

1

5

Small-scale

0.479

High

868926

ATX1
Ataxin-1

1

0

High-throughput

0.458

High

964604

Q3UQ17
Zinc finger and BTB domain containing 16

1

0

Small-scale

0.458

High

964606

CLU
Clustered mitochondria protein homolog

1

0

High-throughput

0.458

High

964607

Q5SXC4
Vascular endothelial zinc finger 1

1

0

Small-scale

0.458

High

964617

ATG5
Autophagy protein 5

1

0

Small-scale

0.458

High

964622

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

1

High-throughput

0.457

High

93507

ARI1B
AT-rich interactive domain-containing protein 1B

1

3

Small-scale

0.445

High

521439

NR4A1
Nuclear receptor subfamily 4 group A member 1

1

8

Small-scale

0.445

High

828451

CENPC
Centromere protein C

1

2

High-throughput

0.445

High

857569

HMGA2
High mobility group protein HMGI-C

1

2

High-throughput

0.445

High

964602

STING
Stimulator of interferon genes protein

1

1

High-throughput

0.445

High

964620

AIRE
Autoimmune regulator

1

9

Small-scale

0.445

High

964614

ARRB1
Beta-arrestin-1

1

0

High-throughput

0.438

High


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Last updated: 15 Jul 2024