HitPredict

Interactor 1: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Interactor 2: HPBP1 (Q9NZL4)
Hsp70-binding protein 1 (HspBP1) (Heat shock protein-binding protein 1) (Hsp70-binding protein 2) (HspBP2) (Hsp70-interacting protein 1) (Hsp70-interacting protein 2)
Gene: HSPBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned1853
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005615 - extracellular space GO:0005783 - endoplasmic reticulum GO:0031398 - positive regulation of protein ubiquitination GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 2527 Hs			1 359
+	Hs
		73067 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		B4DWX3_HUMAN (71-301): 3.47e-24: 105: 18.03
+	Hs
		134913 LRRK2_HUMAN (1-2527): 0: 3008: 99.72		IMA3_HUMAN (57-331): 3.72e-21: 96.5: 14.39
+	Hs
		201450 M3K7_HUMAN (1869-2132): 8.36e-23: 107: 28.83		HPBP1_HUMAN (1-359): 3.87e-108: 322: 100.00