Protein: GSE1
Genetic suppressor element 1

Gene: GSE1
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q14687

Gene Ontology (top 5):
GO:0001701 - in utero embryonic development
GO:0001890 - placenta development
GO:0010467 - gene expression

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1130671

RCOR3
REST corepressor 3

7

2

High-throughput

0.688

High

1109724

HDAC1
Histone deacetylase 1

8

1

High-throughput

0.688

High

520045

ANDR
Androgen receptor

4

2

Small-scale

0.676

High

1130648

HDAC2
Histone deacetylase 2

5

1

Small-scale

0.654

High

246602

KDM1A
Lysine-specific histone demethylase 1A

5

1

Small-scale

0.647

High

587082

ITF2
Transcription factor 4

3

1

High-throughput

0.616

High

1130666

HM20A
High mobility group protein 20A

3

2

High-throughput

0.616

High

1130670

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

3

3

High-throughput

0.609

High

1055218

MTG8
Protein CBFA2T1

2

2

High-throughput

0.590

High

142996

NFIB
Nuclear factor 1 B-type

2

3

High-throughput

0.584

High

404059

GCR
Glucocorticoid receptor

2

3

Small-scale

0.584

High

1087741

NFIA
Nuclear factor 1 A-type

2

4

High-throughput

0.584

High

1130678

RCOR1
REST corepressor 1

2

2

High-throughput

0.558

High

1130656

LENG8
Leukocyte receptor cluster member 8

2

2

High-throughput

0.553

High

473989

NFIC
Nuclear factor 1 C-type

2

3

High-throughput

0.533

High

872330

SOX2
Transcription factor SOX-2

2

4

Small-scale

0.533

High

1130618

NFIX
Nuclear factor 1 X-type

2

4

High-throughput

0.533

High

1130657

RANB9
Ran-binding protein 9

2

1

Small-scale

0.533

High

1130617

GSE1
Genetic suppressor element 1

1

0

High-throughput

0.518

High

1130673

LHX3
LIM/homeobox protein Lhx3

1

0

High-throughput

0.513

High

590428

GATA1
Erythroid transcription factor

1

2

High-throughput

0.479

High

662576

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

2

High-throughput

0.479

High

775840

HNF1B
Hepatocyte nuclear factor 1-beta

1

4

High-throughput

0.479

High

1130621

TBR1
T-box brain protein 1

1

1

High-throughput

0.479

High

1130643

SP7
Transcription factor Sp7

1

1

High-throughput

0.479

High

60236

A2RRN7
CADPS protein

1

1

High-throughput

0.470

High

289149

PRDM1
PR domain zinc finger protein 1

1

0

High-throughput

0.458

High

413835

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

1113118

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1120849

DGCR6
Protein DGCR6

1

1

High-throughput

0.439

High

1130681

CAPS1
Calcium-dependent secretion activator 1

1

1

High-throughput

0.439

High

124599

EYA2
Protein phosphatase EYA2

1

2

High-throughput

0.437

High

181513

TBXT
T-box transcription factor T

1

1

High-throughput

0.437

High

225000

TLX3
T-cell leukemia homeobox protein 3

1

4

High-throughput

0.437

High

226550

TLX2
T-cell leukemia homeobox protein 2

1

2

High-throughput

0.437

High

239954

SOX15
Transcription factor SOX-15

1

5

High-throughput

0.437

High

270246

MTG16
Protein CBFA2T3

1

1

Small-scale

0.437

High

341568

EYA4
Protein phosphatase EYA4

1

2

High-throughput

0.437

High

540865

ERG
Transcriptional regulator ERG

1

1

High-throughput

0.437

High

581659

MYOD1
Myoblast determination protein 1

1

1

High-throughput

0.437

High

587471

TFE2
Transcription factor E2-alpha

1

1

High-throughput

0.437

High

639732

TAF1
Transcription initiation factor TFIID subunit 1

1

3

High-throughput

0.437

High

659228

SP100
Nuclear autoantigen Sp-100

1

3

High-throughput

0.437

High

662226

PAX7
Paired box protein Pax-7

1

5

High-throughput

0.437

High

662425

GATA2
Endothelial transcription factor GATA-2

1

2

High-throughput

0.437

High

685196

PAX6
Paired box protein Pax-6

1

4

High-throughput

0.437

High

725254

TLX1
T-cell leukemia homeobox protein 1

1

2

High-throughput

0.437

High

776069

SOX5
Transcription factor SOX-5

1

4

High-throughput

0.437

High

776194

SOX6
Transcription factor SOX-6

1

4

High-throughput

0.437

High

833941

HNF4A
Hepatocyte nuclear factor 4-alpha

1

1

High-throughput

0.437

High

879092

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

2

High-throughput

0.437

High

938446

PAX9
Paired box protein Pax-9

1

4

High-throughput

0.437

High

944653

KLF3
Krueppel-like factor 3

1

2

High-throughput

0.437

High

1040049

PAX2
Paired box protein Pax-2

1

4

High-throughput

0.437

High

1047972

TLE3
Transducin-like enhancer protein 3

1

1

High-throughput

0.437

High

1056605

PAX8
Paired box protein Pax-8

1

4

High-throughput

0.437

High

1091212

FOXI1
Forkhead box protein I1

1

1

High-throughput

0.437

High

1091281

FOXL1
Forkhead box protein L1

1

1

High-throughput

0.437

High

1118706

KLF5
Krueppel-like factor 5

1

2

High-throughput

0.437

High

1130622

ISX
Intestine-specific homeobox

1

2

High-throughput

0.437

High

1130626

RN123
E3 ubiquitin-protein ligase RNF123

1

1

High-throughput

0.437

High

1130639

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.437

High

1130646

PHIP
PH-interacting protein

1

1

High-throughput

0.437

High

1130650

PF21A
PHD finger protein 21A

1

1

High-throughput

0.437

High

1130659

FEV
Protein FEV

1

1

High-throughput

0.437

High

1130661

MTA3
Metastasis-associated protein MTA3

1

2

High-throughput

0.437

High

1130663

FOXQ1
Forkhead box protein Q1

1

2

High-throughput

0.437

High

1130668

RNC
Ribonuclease 3

1

1

High-throughput

0.437

High

1130676

KLF15
Krueppel-like factor 15

1

2

High-throughput

0.437

High

1130680

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

5

High-throughput

0.437

High

1130684

NR2E1
Nuclear receptor subfamily 2 group E member 1

1

1

Small-scale

0.437

High

1130687

X5DP20
DiGeorge syndrome critical region 6 isoform D

1

1

High-throughput

0.417

High

1063251

GOGA2
Golgin subfamily A member 2

6

0

High-throughput

0.384

High

1130630

CA094
Uncharacterized protein C1orf94

4

0

High-throughput

0.368

High

1130644

DOK4
Docking protein 4

4

0

High-throughput

0.360

High

571976

TRI27
Zinc finger protein RFP

3

0

High-throughput

0.348

High

349999

SNAI1
Zinc finger protein SNAI1

3

0

High-throughput

0.347

High

426953

FGF1
Fibroblast growth factor 1

3

0

High-throughput

0.347

High

1130620

TRIP6
Thyroid receptor-interacting protein 6

2

0

High-throughput

0.337

High

1130645

TEKT4
Tektin-4

2

0

High-throughput

0.337

High

1130619

RBP1
RalA-binding protein 1

2

0

High-throughput

0.334

High

1130649

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.329

High

1130629

L2GL2
LLGL scribble cell polarity complex component 2

2

0

High-throughput

0.328

High

1130651

F136A
Protein FAM136A

2

0

High-throughput

0.328

High

1130669

HAOX2
2-Hydroxyacid oxidase 2

2

0

High-throughput

0.328

High

1090645

TRAF2
TNF receptor-associated factor 2

2

0

High-throughput

0.316

High

1130654

ZMY19
Zinc finger MYND domain-containing protein 19

2

0

High-throughput

0.316

High

1130662

CAR10
Caspase recruitment domain-containing protein 10

2

0

High-throughput

0.316

High

1130672

TFP11
Tuftelin-interacting protein 11

2

0

High-throughput

0.316

High

1130655

CEP63
Centrosomal protein of 63 kDa

2

0

High-throughput

0.307

High

1130658

CDC5L
Cell division cycle 5-like protein

2

0

High-throughput

0.307

High

1130677

TNIK
TRAF2 and NCK-interacting protein kinase

2

0

High-throughput

0.300

High

1130638

CF206
Cilia- and flagella-associated protein 206

1

0

High-throughput

0.299

High

279367

TULP3
Tubby-related protein 3

1

0

High-throughput

0.282

High

558135

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.282

High

1130625

RBM48
RNA-binding protein 48

1

0

High-throughput

0.282

High

1130633

NUD18
8-oxo-dGDP phosphatase NUDT18

1

0

High-throughput

0.282

High

1130641

CEP70
Centrosomal protein of 70 kDa

1

0

High-throughput

0.282

High

384413

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.279

Low

691739

MK03
Mitogen-activated protein kinase 3

1

0

High-throughput

0.279

Low

1130623

EFMT2
EEF1A lysine methyltransferase 2

1

0

High-throughput

0.279

Low

1130652

ZN524
Zinc finger protein 524

1

0

High-throughput

0.279

Low

1130660

OVOL2
Transcription factor Ovo-like 2

1

0

High-throughput

0.279

Low

1130664

SHRPN
Sharpin

1

0

High-throughput

0.279

Low

1130675

SMBT1
Scm-like with four MBT domains protein 1

1

0

High-throughput

0.279

Low

1130685

ASB3
Ankyrin repeat and SOCS box protein 3

1

0

High-throughput

0.279

Low

1006405

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.261

Low

1087384

GRSF1
G-rich sequence factor 1

1

0

Small-scale

0.251

Low

1130624

EXOS6
Exosome complex component MTR3

1

0

High-throughput

0.251

Low

129082

MEN1
Menin

1

0

High-throughput

0.249

Low

130466

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.249

Low

174512

TRI66
Tripartite motif-containing protein 66

1

0

High-throughput

0.249

Low

262515

MCE1
mRNA-capping enzyme

1

0

High-throughput

0.249

Low

372037

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

378490

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.249

Low

411936

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

703139

TEAD1
Transcriptional enhancer factor TEF-1

1

0

High-throughput

0.249

Low

886863

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.249

Low

1004566

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1047008

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

0

Small-scale

0.249

Low

1052868

HME1
Homeobox protein engrailed-1

1

0

High-throughput

0.249

Low

1083357

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

0

High-throughput

0.249

Low

1130627

CP135
Centrosomal protein of 135 kDa

1

0

High-throughput

0.249

Low

1130628

H2B2C
Putative histone H2B type 2-C

1

0

High-throughput

0.249

Low

1130631

BCOR
BCL-6 corepressor

1

0

Small-scale

0.249

Low

1130632

SYNE3
Nesprin-3

1

0

High-throughput

0.249

Low

1130635

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1130636

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

0

High-throughput

0.249

Low

1130637

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.249

Low

1130640

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1130642

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.249

Low

1130647

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.249

Low

1130653

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.249

Low

1130665

GCM1
Chorion-specific transcription factor GCMa

1

0

High-throughput

0.249

Low

1130667

ALG13
UDP-N-acetylglucosamine transferase subunit ALG13

1

0

High-throughput

0.249

Low

1130674

ZMYM2
Zinc finger MYM-type protein 2

1

0

High-throughput

0.249

Low

1130679

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low

1130682

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.249

Low

1130683

NINL
Ninein-like protein

1

0

High-throughput

0.249

Low

1130686

INSI2
Insulin-induced gene 2 protein

1

0

High-throughput

0.249

Low

1126680

BECN1
Beclin-1

1

0

Small-scale

0.238

Low

1130634

SV2B
Synaptic vesicle glycoprotein 2B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025