Interactor 1: ODBB (Q5SLR3)
2-oxoisovalerate dehydrogenase subunit beta (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component beta chain) (BCKDH E1-beta)
Gene: TTHA0230

Interactor 2: ODBA (Q5SLR4)
2-oxoisovalerate dehydrogenase subunit alpha (EC 1.2.4.4) (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha)
Gene: TTHA0229

Species: Thermus thermophilus HB8

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 15033367
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains E1_dh~Transket_pyr, E1_dh~Transketolase_C
Common GO terms GO:0003863 - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity
GO:0009083 - branched-chain amino acid catabolic process
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 324
Tt

1 367
+ Hs
+ Mm
+ Hs
+ At
+ Dm
+ Dm
+ Ce
+ At
+ Hs
+ Gs
+ Sc
+ Ce
+ Ce
+ Pp
+ Mp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024