Protein: CSTF3
Cleavage stimulation factor subunit 3 (CF-1 77 kDa subunit) (Cleavage stimulation factor 77 kDa subunit) (CSTF 77 kDa subunit) (CstF-77)

Gene: CSTF3
Organism: Homo sapiens
Interactions: 110
UniProt ID: Q12996

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005848 - mRNA cleavage stimulating factor complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1092352

CSTFT
Cleavage stimulation factor subunit 2 tau variant

3

13

High-throughput

0.855

High

750413

CSTF2
Cleavage stimulation factor subunit 2

3

12

Small-scale

0.853

High

1083345

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

2

5

Small-scale

0.768

High

1050281

CSTF1
Cleavage stimulation factor subunit 1

2

20

Small-scale

0.737

High

1092311

SNW1
SNW domain-containing protein 1

1

8

High-throughput

0.691

High

1092347

CDC5L
Cell division cycle 5-like protein

1

12

High-throughput

0.691

High

667285

RPB1
DNA-directed RNA polymerase II subunit RPB1

3

5

Small-scale

0.664

High

986383

PPIA
Peptidyl-prolyl cis-trans isomerase A

3

7

High-throughput

0.640

High

1092326

FIP1
Pre-mRNA 3'-end-processing factor FIP1

2

3

Small-scale

0.619

High

1092342

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

20

High-throughput

0.618

High

537071

HSP7C
Heat shock cognate 71 kDa protein

2

4

High-throughput

0.611

High

1092338

SYMPK
Symplekin

2

1

High-throughput

0.611

High

1092346

CCNL2
Cyclin-L2

2

1

High-throughput

0.611

High

708959

T2EB
Transcription initiation factor IIE subunit beta

2

0

High-throughput

0.602

High

241542

PRKN
E3 ubiquitin-protein ligase parkin

2

9

High-throughput

0.584

High

396012

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

1092323

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.553

High

341932

CEP43
Centrosomal protein 43

1

1

High-throughput

0.536

High

484514

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

541984

TOP1
DNA topoisomerase 1

1

4

High-throughput

0.536

High

930868

HSP72
Heat shock-related 70 kDa protein 2

1

4

High-throughput

0.536

High

1092312

CUL3
Cullin-3

1

14

High-throughput

0.536

High

1092318

RNPS1
RNA-binding protein with serine-rich domain 1

1

20

High-throughput

0.536

High

1092320

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

10

High-throughput

0.536

High

1092333

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.536

High

1092345

RBM14
RNA-binding protein 14

1

11

High-throughput

0.536

High

1092354

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

2

High-throughput

0.536

High

1092362

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

3

High-throughput

0.536

High

212657

DAPK3
Death-associated protein kinase 3

1

4

High-throughput

0.515

High

1040278

DYST
Dystonin

1

2

High-throughput

0.515

High

1092364

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.515

High

1092325

CDC73
Parafibromin

1

0

Small-scale

0.513

High

1092355

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

822636

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

346990

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.489

High

566971

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

3

High-throughput

0.489

High

1092349

FEM1A
Protein fem-1 homolog A

1

1

High-throughput

0.489

High

1092367

WIF1
Wnt inhibitory factor 1

1

2

High-throughput

0.489

High

129031

MEN1
Menin

1

6

High-throughput

0.479

High

142976

NFIB
Nuclear factor 1 B-type

1

6

High-throughput

0.479

High

247869

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

259876

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

315529

RECQ4
ATP-dependent DNA helicase Q4

1

17

High-throughput

0.479

High

337344

PARN
Poly(A)-specific ribonuclease PARN

1

2

High-throughput

0.479

High

345738

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

16

High-throughput

0.479

High

363207

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

472694

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

17

High-throughput

0.479

High

473960

NFIC
Nuclear factor 1 C-type

1

10

High-throughput

0.479

High

485103

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

11

Small-scale

0.479

High

519996

ANDR
Androgen receptor

1

18

High-throughput

0.479

High

549135

CDK4
Cyclin-dependent kinase 4

1

4

High-throughput

0.479

High

588575

RFA2
Replication protein A 32 kDa subunit

1

6

High-throughput

0.479

High

695333

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

731245

STIP1
Stress-induced-phosphoprotein 1

1

9

High-throughput

0.479

High

768069

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

897781

CDK9
Cyclin-dependent kinase 9

1

5

High-throughput

0.479

High

904659

MECP2
Methyl-CpG-binding protein 2

1

5

High-throughput

0.479

High

998264

H31
Histone H3.1

1

5

High-throughput

0.479

High

1067247

EP300
Histone acetyltransferase p300

1

6

High-throughput

0.479

High

1087718

NFIA
Nuclear factor 1 A-type

1

10

High-throughput

0.479

High

1088821

TP53B
TP53-binding protein 1

1

4

High-throughput

0.479

High

1092309

BIRC3
Baculoviral IAP repeat-containing protein 3

1

6

High-throughput

0.479

High

1092310

SQSTM
Sequestosome-1

1

2

High-throughput

0.479

High

1092313

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

1

High-throughput

0.479

High

1092315

NFIX
Nuclear factor 1 X-type

1

9

High-throughput

0.479

High

1092317

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

1092319

ELAV1
ELAV-like protein 1

1

7

High-throughput

0.479

High

1092329

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

3

Small-scale

0.479

High

1092331

SMC5
Structural maintenance of chromosomes protein 5

1

7

High-throughput

0.479

High

1092334

TNIP2
TNFAIP3-interacting protein 2

1

1

High-throughput

0.479

High

1092337

ESR2
Estrogen receptor beta

1

18

High-throughput

0.479

High

1092339

CELF1
CUGBP Elav-like family member 1

1

10

High-throughput

0.479

High

1092340

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

1092341

DCPS
m7GpppX diphosphatase

1

3

High-throughput

0.479

High

1092343

ZBT10
Zinc finger and BTB domain-containing protein 10

1

4

Small-scale

0.479

High

1092348

MACD1
ADP-ribose glycohydrolase MACROD1

1

2

Small-scale

0.479

High

1092356

TLS1
Splicing factor C9orf78

1

2

High-throughput

0.479

High

1092357

WWOX
WW domain-containing oxidoreductase

1

2

High-throughput

0.479

High

1092358

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

3

Small-scale

0.479

High

1092360

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

1092361

TBK1
Serine/threonine-protein kinase TBK1

1

3

High-throughput

0.479

High

1092363

FZR1
Fizzy-related protein homolog

1

19

High-throughput

0.479

High

1092365

FAF1
FAS-associated factor 1

1

2

High-throughput

0.479

High

1092314

SLBP
Histone RNA hairpin-binding protein

1

0

Small-scale

0.458

High

1092336

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1092351

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

191325

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

3

High-throughput

0.445

High

446960

NPM
Nucleophosmin

1

5

Small-scale

0.445

High

1092321

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

4

High-throughput

0.445

High

157307

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.437

High

411837

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.437

High

1092316

CUL7
Cullin-7

1

2

High-throughput

0.437

High

1092328

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

1092335

NUDC2
NudC domain-containing protein 2

1

1

High-throughput

0.437

High

1092353

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.437

High

1092359

HECW2
E3 ubiquitin-protein ligase HECW2

1

5

High-throughput

0.437

High

886810

CEBPA
CCAAT/enhancer-binding protein alpha

1

8

High-throughput

0.408

High

1092324

NCLX
Mitochondrial sodium/calcium exchanger protein

1

1

High-throughput

0.407

High

1092344

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

562718

BMP1
Bone morphogenetic protein 1

2

0

High-throughput

0.328

High

416016

CP1A1
Cytochrome P450 1A1

2

0

High-throughput

0.318

High

652310

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.279

Low

663492

PRPH2
Peripherin-2

1

0

High-throughput

0.279

Low

935725

MFAP4
Microfibril-associated glycoprotein 4

1

0

High-throughput

0.279

Low

1092322

SYT6
Synaptotagmin-6

1

0

High-throughput

0.279

Low

1092330

C1QL4
Complement C1q-like protein 4

1

0

High-throughput

0.279

Low

1092332

MESH1
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

1

0

High-throughput

0.279

Low

1092366

KLH20
Kelch-like protein 20

1

0

High-throughput

0.279

Low

1092327

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1092350

UBAC1
Ubiquitin-associated domain-containing protein 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025