HitPredict

Interactor 1: M9NFI9 (M9NFI9)
Spinophilin, isoform J
Gene: Spn

Interactor 2: Q7KJ08 (Q7KJ08)
Anaplastic lymphoma kinase, isoform A (EC 2.7.10.1) (Anaplastic lymphoma kinase, isoform B) (Receptor protein tyrosine kinase ALK splice variant A)
Gene: Alk

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	25294943
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SAM_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2148 Dm			1 1701
+	Hs
		159214 CSKP_HUMAN (1025-1643): 1.07e-65: 244: 12.16		EPHA7_HUMAN (758-1568): 2.24e-164: 528: 18.96
+	Hs
		876391 AFAD_HUMAN (1070-1697): 9.8e-57: 221: 15.72		EPHA7_HUMAN (758-1568): 2.24e-164: 528: 18.96
+	Hs
		159179 CSKP_HUMAN (1025-1643): 1.07e-65: 244: 12.16		EPHA4_HUMAN (759-1571): 2.14e-155: 503: 17.91
+	Hs
		665569 AFAD_HUMAN (1070-1697): 9.8e-57: 221: 15.72		EPHB2_HUMAN (759-1601): 8.71e-163: 525: 17.41
+	Hs
		665186 AFAD_HUMAN (1070-1697): 9.8e-57: 221: 15.72		EPHA2_HUMAN (759-1551): 1.79e-153: 497: 18.08
+	Hs
		872402 AFAD_HUMAN (1070-1697): 9.8e-57: 221: 15.72		EPHB3_HUMAN (760-1566): 1.36e-150: 490: 18.29
+	Hs
		665589 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		EPHB2_HUMAN (759-1601): 8.71e-163: 525: 17.41
+	Hs
		665393 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		EPHA3_HUMAN (752-1554): 2.19e-162: 522: 18.33
+	Hs
		666588 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		LTK_HUMAN (661-1531): 3.63e-163: 520: 34.01
+	Hs
		872431 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		EPHA5_HUMAN (759-1554): 2.19e-158: 513: 18.22
+	Hs
		665228 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		EPHA2_HUMAN (759-1551): 1.79e-153: 497: 18.08
+	Hs
		159144 CSKP_HUMAN (1025-1643): 1.07e-65: 244: 12.16		FGFR1_HUMAN (1077-1517): 1.2e-122: 408: 31.35
+	Hs
		434182 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		RET_HUMAN (878-1571): 2.03e-135: 452: 21.70
+	Hs
		507970 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		FGFR1_HUMAN (1077-1517): 1.2e-122: 408: 31.35
+	Hs
		561393 RHG21_HUMAN (1234-2031): 4.2e-56: 218: 12.88		FER_HUMAN (1177-1461): 1.14e-69: 254: 45.52
+	Hs
		159135 CSKP_HUMAN (1025-1643): 1.07e-65: 244: 12.16		NTRK1_HUMAN (1164-1465): 1.07e-59: 223: 38.56
+	Hs
		384568 AFAD_HUMAN (1070-1697): 9.8e-57: 221: 15.72		NTRK1_HUMAN (1164-1465): 1.07e-59: 223: 38.56
+	Rn
		94277 F1LW22_RAT (940-1690): 5.76e-50: 197: 14.27		INSR_RAT (1187-1460): 4.9e-64: 243: 42.81
+	Mm
		546326 AFAD_MOUSE (1070-1728): 3.48e-54: 212: 15.71		NTRK2_MOUSE (1167-1464): 7.45e-60: 224: 38.71
+	Hs
		384744 PTN13_HUMAN (1045-1906): 1.08e-41: 171: 12.59		NTRK1_HUMAN (1164-1465): 1.07e-59: 223: 38.56