HitPredict

Interactor 1: C2D1B (Q5T0F9)
Coiled-coil and C2 domain-containing protein 1B (Five prime repressor element under dual repression-binding protein 2) (FRE under dual repression-binding protein 2) (Freud-2)
Gene: CC2D1B

Interactor 2: H2B1M (Q99879)
Histone H2B type 1-M (Histone H2B.e) (H2B/e)
Gene: H2BC14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Hs			1 126
+	Hs
		1087177 C2D1B_HUMAN (1-858): 1.67e-144: 449: 100.00		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		1132379 C2D1B_HUMAN (1-858): 1.67e-144: 449: 100.00		H2B1H_HUMAN (1-126): 6.81e-56: 171: 96.03
+	Hs
		886125 C2D1B_HUMAN (1-858): 1.67e-144: 449: 100.00		H2B1D_HUMAN (1-126): 2.86e-55: 170: 96.83
+	Hs
		1158633 C2D1A_HUMAN (6-855): 1.16e-100: 336: 42.47		H2B1H_HUMAN (1-126): 6.81e-56: 171: 96.03
+	Hs
		1274409 ASPP1_HUMAN (111-544): 5.73e-21: 100: 12.85		H2B1H_HUMAN (1-126): 6.81e-56: 171: 96.03
+	Hs
		1056847 MDC1_HUMAN (5-610): 3.28e-14: 79.4: 8.40		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		1056919 MDC1_HUMAN (5-610): 3.28e-14: 79.4: 8.40		H2B1H_HUMAN (1-126): 6.81e-56: 171: 96.03
+	Hs
		707631 MDC1_HUMAN (5-610): 3.28e-14: 79.4: 8.40		H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83
+	Hs
		918364 MDC1_HUMAN (5-610): 3.28e-14: 79.4: 8.40		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		707690 KMT2C_HUMAN (67-585): 3.79e-11: 69.3: 8.30		H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83
+	Hs
		918533 KMT2C_HUMAN (67-585): 3.79e-11: 69.3: 8.30		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		617962 TITIN_HUMAN (69-503): 2.16e-10: 67: 12.74		H2B1O_HUMAN (1-126): 3.65e-56: 172: 95.24
+	Hs
		1087338 CHAP1_HUMAN (8-418): 1.11e-10: 67.5: 9.18		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		707710 CHAP1_HUMAN (8-418): 1.11e-10: 67.5: 9.18		H2B1B_HUMAN (1-126): 1.31e-55: 171: 96.83
+	Hs
		918607 CHAP1_HUMAN (8-418): 1.11e-10: 67.5: 9.18		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		1087299 TITIN_HUMAN (69-503): 2.16e-10: 67: 12.74		H2B2E_HUMAN (1-126): 6.59e-56: 171: 96.03
+	Hs
		241595 TITIN_HUMAN (69-503): 2.16e-10: 67: 12.74		H2B1K_HUMAN (1-126): 1.42e-55: 171: 96.03
+	Hs
		883041 TITIN_HUMAN (69-503): 2.16e-10: 67: 12.74		H2BFS_HUMAN (1-126): 1.37e-55: 171: 94.44
+	Hs
		918561 TITIN_HUMAN (69-503): 2.16e-10: 67: 12.74		H2B1C_HUMAN (1-126): 1.23e-55: 171: 96.83
+	Hs
		886166 TITIN_HUMAN (69-503): 2.16e-10: 67: 12.74		H2B1D_HUMAN (1-126): 2.86e-55: 170: 96.83