HitPredict

Interactor 1: LCE1C (Q5T751)
Late cornified envelope protein 1C (Late envelope protein 3)
Gene: LCE1C

Interactor 2: KRA44 (Q9BYR3)
Keratin-associated protein 4-4 (Keratin-associated protein 4-13) (Keratin-associated protein 4.13) (Keratin-associated protein 4.4) (Ultrahigh sulfur keratin-associated protein 4.13) (Ultrahigh sulfur keratin-associated protein 4.4)
Gene: KRTAP4-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 Hs			1 166
+	Hs
		1134501 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR412_HUMAN (1-166): 1.13e-30: 111: 63.18
+	Hs
		887372 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR122_HUMAN (28-166): 1.43e-26: 99.4: 34.29
+	Hs
		887375 LCE1B_HUMAN (1-118): 1.23e-49: 155: 96.61		KR122_HUMAN (28-166): 1.43e-26: 99.4: 34.29
+	Hs
		889780 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR109_HUMAN (3-156): 1.49e-24: 97.9: 33.14
+	Hs
		1134505 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR411_HUMAN (4-131): 1.38e-24: 95.9: 43.14
+	Hs
		1134508 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KRA42_HUMAN (29-166): 2.7e-25: 95.9: 68.12
+	Hs
		889061 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR105_HUMAN (14-166): 1.68e-22: 92.1: 33.33
+	Hs
		1134506 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KRA45_HUMAN (3-166): 4.76e-19: 81.3: 46.95
+	Hs
		889509 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR108_HUMAN (19-165): 2.65e-18: 80.9: 28.81
+	Hs
		1134503 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KRA93_HUMAN (2-151): 2.17e-17: 76.3: 37.42
+	Hs
		888702 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR101_HUMAN (32-166): 6.51e-15: 72: 30.22
+	Hs
		1134502 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KRA98_HUMAN (2-126): 1.54e-13: 66.3: 35.20
+	Hs
		887733 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR10A_HUMAN (19-136): 7.33e-12: 63.2: 34.17
+	Hs
		1134504 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KRA92_HUMAN (3-116): 3.48e-12: 62.8: 43.36
+	Hs
		473291 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KRA23_HUMAN (49-166): 5.02e-11: 59: 38.98
+	Hs
		473296 LCE1B_HUMAN (1-118): 1.23e-49: 155: 96.61		KRA23_HUMAN (49-166): 5.02e-11: 59: 38.98
+	Hs
		887314 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR121_HUMAN (51-137): 6.05e-10: 55.1: 31.03
+	Hs
		887318 LCE1B_HUMAN (1-118): 1.23e-49: 155: 96.61		KR121_HUMAN (51-137): 6.05e-10: 55.1: 31.03
+	Hs
		888550 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR123_HUMAN (34-126): 2.53e-09: 53.6: 31.18
+	Hs
		888648 LCE1C_HUMAN (1-118): 3.17e-50: 156: 100.00		KR124_HUMAN (23-136): 4.09e-09: 53.2: 36.52