HitPredict

Interactor 1: FHL5 (Q5TD97)
Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP-responsive element modulator in testis) (Activator of CREM in testis)
Gene: FHL5

Interactor 2: PDLI7 (Q9NR12)
PDZ and LIM domain protein 7 (LIM mineralization protein) (LMP) (Protein enigma)
Gene: PDLIM7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0030018 - Z disc GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 284 Hs			1 457
+	Hs
		238992 LPXN_HUMAN (99-284): 9.12e-49: 167: 26.88		PDLI7_HUMAN (1-457): 2.02e-91: 286: 100.00
+	Hs
		823508 PAXI_HUMAN (102-284): 5.47e-56: 191: 26.23		LIMD1_HUMAN (78-457): 6.82e-53: 190: 17.84
+	Hs
		238982 LPXN_HUMAN (99-284): 9.12e-49: 167: 26.88		LPP_HUMAN (85-457): 5.09e-56: 197: 19.02
+	Hs
		238998 LPXN_HUMAN (99-284): 9.12e-49: 167: 26.88		LIMD1_HUMAN (78-457): 6.82e-53: 190: 17.84
+	Hs
		823353 PAXI_HUMAN (102-284): 5.47e-56: 191: 26.23		PAXI_HUMAN (185-396): 1.45e-33: 135: 21.23
+	Hs
		200167 PAXI_HUMAN (102-284): 5.47e-56: 191: 26.23		TGFI1_HUMAN (71-397): 1.78e-33: 133: 17.43
+	Hs
		549178 FHL5_HUMAN (1-284): 7.23e-69: 216: 100.00		ZN250_HUMAN (362-457): 4.28e-23: 103: 6.25
+	Hs
		816231 PAXI_HUMAN (102-284): 5.47e-56: 191: 26.23		LIMS1_HUMAN (298-452): 6.05e-14: 74.3: 24.54
+	Hs
		823405 PAXI_HUMAN (102-284): 5.47e-56: 191: 26.23		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87
+	Ce
		107727 PXL1_CAEEL (102-284): 4.81e-50: 172: 26.23		G5EFL5_CAEEL (1-338): 5.65e-16: 82.8: 15.54
+	Hs
		823403 PAXI_HUMAN (102-284): 5.47e-56: 191: 26.23		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Ce
		107596 PXL1_CAEEL (102-284): 4.81e-50: 172: 26.23		G5EFG1_CAEEL (1-338): 1.06e-13: 75.5: 14.66
+	Hs
		238953 LPXN_HUMAN (99-284): 9.12e-49: 167: 26.88		LIMS1_HUMAN (298-452): 6.05e-14: 74.3: 24.54
+	Hs
		238967 LPXN_HUMAN (99-284): 9.12e-49: 167: 26.88		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87
+	Hs
		1044587 FHL3_HUMAN (67-283): 1.13e-42: 148: 28.77		FHL3_HUMAN (304-449): 9.17e-16: 79.3: 28.38
+	Hs
		238966 LPXN_HUMAN (99-284): 9.12e-49: 167: 26.88		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42
+	Hs
		1044598 FHL3_HUMAN (67-283): 1.13e-42: 148: 28.77		ZYX_HUMAN (74-336): 8.74e-11: 66.1: 13.87
+	Hs
		1044595 FHL3_HUMAN (67-283): 1.13e-42: 148: 28.77		TRIP6_HUMAN (396-457): 6.89e-09: 59.7: 27.42