HitPredict

Interactor 1: Q5U0X8 (Q5U0X8)
LD10780p
Gene: DmelCG12325

Interactor 2: Q9VFV8 (Q9VFV8)
LD47749p
Gene: DmelCG9799

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	25242320, 22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Utp12~Utp21, ANAPC4_WD40~WD40
Common GO terms	GO:0032040 - small-subunit processome GO:0034388 - Pwp2p-containing subcomplex of 90S preribosome
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 949 Dm			1 922
+	Hs
		1070016 PWP2_HUMAN (1-908): 2.37e-170: 522: 46.65		WDR36_HUMAN (2-919): 0: 553: 38.22
+	Hs
		1016302 TBL3_HUMAN (107-889): 3.1e-114: 371: 12.79		WDR36_HUMAN (2-919): 0: 553: 38.22
+	Sc
		635645 PWP2_YEAST (1-947): 6.2e-158: 489: 31.60		UTP21_YEAST (9-919): 5.04e-132: 421: 27.20
+	Sc
		635548 PWP2_YEAST (1-947): 6.2e-158: 489: 31.60		PWP2_YEAST (6-650): 1.11e-74: 265: 12.33
+	Hs
		903379 WDR5_HUMAN (554-882): 5.22e-57: 201: 14.41		WDR36_HUMAN (2-919): 0: 553: 38.22
+	Sc
		635644 PWP2_YEAST (1-947): 6.2e-158: 489: 31.60		UTP13_YEAST (2-568): 2.85e-65: 237: 10.52
+	Dm
		1137156 Q5U0X8_DROME (1-934): 0: 577: 100.00		Q7JQT9_DROME (6-185): 5.22e-25: 113: 12.90
+	Dm
		1137157 Q5U0X8_DROME (1-934): 0: 577: 100.00		Q9VE98_DROME (436-722): 5.78e-23: 107: 9.83
+	Hs
		1016282 PWP2_HUMAN (1-908): 2.37e-170: 522: 46.65		TBL3_HUMAN (10-230): 2.98e-39: 158: 14.46
+	Sc
		985835 UTP12_YEAST (1-507): 6.82e-71: 255: 11.89		UTP21_YEAST (9-919): 5.04e-132: 421: 27.20
+	Hs
		1070055 PWP2_HUMAN (1-908): 2.37e-170: 522: 46.65		WDR3_HUMAN (334-746): 4.94e-24: 111: 9.75
+	Sc
		635670 PWP2_YEAST (1-947): 6.2e-158: 489: 31.60		UTP12_YEAST (27-111): 1.47e-09: 64.2: 10.23
+	Hs
		903174 TBL3_HUMAN (107-889): 3.1e-114: 371: 12.79		WDR5_HUMAN (382-700): 2.86e-47: 173: 12.13
+	Sc
		985442 UTP12_YEAST (1-507): 6.82e-71: 255: 11.89		UTP13_YEAST (2-568): 2.85e-65: 237: 10.52
+	Hs
		1016345 TBL3_HUMAN (107-889): 3.1e-114: 371: 12.79		WDR3_HUMAN (334-746): 4.94e-24: 111: 9.75
+	Hs
		903349 WDR5_HUMAN (554-882): 5.22e-57: 201: 14.41		WDR5B_HUMAN (411-699): 4.9e-48: 176: 13.40
+	Hs
		903077 WDR5_HUMAN (554-882): 5.22e-57: 201: 14.41		WDR5_HUMAN (382-700): 2.86e-47: 173: 12.13
+	Hs
		725410 WDR5_HUMAN (554-882): 5.22e-57: 201: 14.41		COPB2_HUMAN (491-752): 1.58e-37: 153: 12.27