HitPredict

Interactor 1: Q5U0Y0 (Q5U0Y0)
LD13852p (Sin3A, isoform B) (Sin3A, isoform C) (Sin3A, isoform E)
Gene: Sin3A

Interactor 2: Q9W410 (Q9W410)
GH06635p
Gene: PF1

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	20566628, 19782028
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PAH~PHF12_MRG_bd
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0070822 - Sin3-type complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2062 Dm			1 878
+	Dm
		1137172 Q5U0Y0_DROME (1-2062): 0: 2620: 100.00		KDM5_DROME (36-110): 3.48e-17: 89.2: 29.49
+	Sp
		143537 PST2_SCHPO (833-1707): 0: 704: 22.73		YAC5_SCHPO (3-118): 1.34e-23: 106: 30.17
+	Hs
		1300603 SIN3A_HUMAN (172-663): 6.77e-65: 245: 22.73		PHF12_HUMAN (3-382): 9.98e-68: 246: 33.33
+	Sc
		609142 SIN3_YEAST (187-489): 4.33e-72: 270: 29.88		RCO1_YEAST (2-418): 6.78e-38: 153: 15.79
+	Hs
		257821 SIN3B_HUMAN (260-676): 2.53e-38: 159: 19.69		PHF12_HUMAN (3-382): 9.98e-68: 246: 33.33
+	Mm
		1130953 SIN3B_MOUSE (260-676): 4.63e-37: 155: 19.78		PHF12_MOUSE (3-382): 7.01e-67: 243: 33.09
+	Mm
		1141048 SIN3A_MOUSE (172-645): 3.08e-65: 246: 22.07		KDM5B_MOUSE (8-112): 3.47e-19: 95.4: 23.15
+	Hs
		1018652 SIN3A_HUMAN (172-663): 6.77e-65: 245: 22.73		CHD3_HUMAN (5-251): 4.45e-18: 92: 14.24
+	Hs
		1059812 SIN3A_HUMAN (172-663): 6.77e-65: 245: 22.73		CHD4_HUMAN (249-345): 2.41e-16: 86.6: 23.71
+	Hs
		1017340 SIN3A_HUMAN (172-663): 6.77e-65: 245: 22.73		BPTF_HUMAN (36-104): 5.78e-16: 85.3: 34.78
+	Hs
		331869 SIN3A_HUMAN (172-663): 6.77e-65: 245: 22.73		NSD2_HUMAN (40-356): 5.01e-12: 72.3: 14.86
+	Hs
		257774 SIN3B_HUMAN (260-676): 2.53e-38: 159: 19.69		CHD3_HUMAN (5-251): 4.45e-18: 92: 14.24
+	At
		1092791 SNL1_ARATH (228-788): 2.08e-44: 179: 19.76		Q1JPM3_ARATH (30-139): 3.44e-12: 71.9: 18.58
+	Hs
		257809 SIN3B_HUMAN (260-676): 2.53e-38: 159: 19.69		CHD5_HUMAN (49-250): 1.03e-17: 90.8: 16.80
+	Hs
		257744 SIN3B_HUMAN (260-676): 2.53e-38: 159: 19.69		KDM5A_HUMAN (36-112): 4.81e-17: 88.5: 28.75
+	Hs
		257817 SIN3B_HUMAN (260-676): 2.53e-38: 159: 19.69		PF21A_HUMAN (101-313): 4.06e-17: 88: 17.49
+	Hs
		257773 SIN3B_HUMAN (260-676): 2.53e-38: 159: 19.69		BPTF_HUMAN (36-104): 5.78e-16: 85.3: 34.78
+	Hs
		257733 SIN3B_HUMAN (260-676): 2.53e-38: 159: 19.69		NSD2_HUMAN (40-356): 5.01e-12: 72.3: 14.86
+	At
		1092790 SNL2_ARATH (238-355): 1.05e-37: 157: 38.14		Q1JPM3_ARATH (30-139): 3.44e-12: 71.9: 18.58
+	At
		99050 F4K8B0_ARATH (238-355): 1.05e-37: 157: 38.14		Q1JPM3_ARATH (30-139): 3.44e-12: 71.9: 18.58