HitPredict

Interactor 1: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated protein 1 light chain 3 beta (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (Microtubule-associated proteins 1A/1B light chain 3B) (MAP1A/MAP1B LC3 B) (MAP1A/MAP1B light chain 3 B)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	33545068, 36574265, 25416956, 31515488
Identification Methods	proximity labelling technology, pull down, two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 636 Hs			1 125
+	Hs
		1138056 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		952173 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328014 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1138015 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		MLP3C_HUMAN (1-120): 2.09e-51: 161: 55.00
+	Hs
		1138039 TNIP1_HUMAN (1-636): 3.59e-77: 260: 100.00		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		1428428 SMC3_HUMAN (278-527): 2.29e-43: 169: 25.09		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		535890 LAMC1_HUMAN (43-539): 7.97e-19: 93.4: 9.38		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		1351971 RBCC1_HUMAN (161-525): 5.88e-15: 81.1: 17.12		MLP3B_HUMAN (1-125): 8.31e-57: 173: 100.00
+	Hs
		1351977 RBCC1_HUMAN (161-525): 5.88e-15: 81.1: 17.12		MLP3A_HUMAN (1-120): 8.25e-55: 168: 82.50
+	Hs
		952258 RBCC1_HUMAN (161-525): 5.88e-15: 81.1: 17.12		GBRL2_HUMAN (7-120): 2.22e-53: 165: 39.47
+	Hs
		328082 RBCC1_HUMAN (161-525): 5.88e-15: 81.1: 17.12		GBRAP_HUMAN (7-121): 6.43e-53: 163: 31.30
+	Hs
		1351964 RBCC1_HUMAN (161-525): 5.88e-15: 81.1: 17.12		MLP3C_HUMAN (1-120): 2.09e-51: 161: 55.00
+	Hs
		1351974 RBCC1_HUMAN (161-525): 5.88e-15: 81.1: 17.12		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Hs
		773013 MYH9_HUMAN (263-570): 8.04e-10: 64.5: 13.64		GBRL1_HUMAN (7-120): 1.51e-51: 160: 32.46
+	Ce
		386960 MYO1_CAEEL (20-531): 1.13e-09: 63.9: 12.24		LGG1_CAEEL (6-120): 5.57e-51: 159: 33.04
+	Ce
		556470 MYO2_CAEEL (148-525): 6.19e-09: 61.5: 16.22		LGG1_CAEEL (6-120): 5.57e-51: 159: 33.04