HitPredict

Interactor 1: MYOME (Q5VU43)
Myomegalin (Cardiomyopathy-associated protein 2) (Phosphodiesterase 4D-interacting protein)
Gene: PDE4DIP

Interactor 2: TLN1 (Q9Y490)
Talin-1
Gene: TLN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.50	0.470

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2346 Hs			1 2541
+	Mm
		1194561 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		MACF1_MOUSE (388-2519): 3.89e-168: 585: 10.87
+	Mm
		640190 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		EZRI_MOUSE (84-680): 3.09e-84: 291: 13.79
+	Hs
		1068562 MYOME_HUMAN (1-2346): 0: 703: 100.00		PLEC_HUMAN (730-2529): 2.6e-23: 111: 12.52
+	Mm
		640209 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		RADI_MOUSE (163-404): 1.04e-56: 210: 22.27
+	Mm
		640197 MYOME_MOUSE (1-2346): 2.71e-171: 585: 69.33		MOES_MOUSE (163-404): 1.39e-51: 195: 23.05
+	Hs
		110636 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		H3BPE1_HUMAN (404-2519): 5.67e-166: 578: 11.16
+	Hs
		255295 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		HIP1R_HUMAN (1834-2532): 3.66e-139: 467: 19.78
+	Hs
		124374 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		HIP1_HUMAN (1798-2532): 2.31e-117: 402: 20.27
+	Hs
		547057 GOGB1_HUMAN (880-2332): 2.13e-37: 157: 10.38		EZRI_HUMAN (84-666): 2.76e-85: 294: 14.65
+	Hs
		1331065 MYH4_HUMAN (1279-2334): 2.89e-32: 140: 9.95		E41L1_HUMAN (16-610): 1.8e-85: 303: 12.87
+	Hs
		640092 CENPE_HUMAN (1-1839): 1.04e-60: 234: 11.33		MOES_HUMAN (163-404): 1.04e-51: 195: 23.05
+	Hs
		640146 CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73		MOES_HUMAN (163-404): 1.04e-51: 195: 23.05
+	Hs
		719681 CENPF_HUMAN (1261-2312): 1.38e-21: 105: 10.69		RADI_HUMAN (84-666): 2.05e-80: 280: 13.96
+	Hs
		640102 GOGB1_HUMAN (880-2332): 2.13e-37: 157: 10.38		MOES_HUMAN (163-404): 1.04e-51: 195: 23.05
+	Hs
		974137 CP250_HUMAN (682-2334): 3.75e-54: 212: 9.73		DYST_HUMAN (422-2075): 3.73e-15: 84.9: 9.63
+	Hs
		640054 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		MOES_HUMAN (163-404): 1.04e-51: 195: 23.05
+	Hs
		724839 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		PLEC_HUMAN (730-2529): 2.6e-23: 111: 12.52
+	Hs
		166696 CE290_HUMAN (10-915): 3.83e-20: 100: 9.92		DYST_HUMAN (422-2075): 3.73e-15: 84.9: 9.63
+	Hs
		725097 MYH10_HUMAN (1099-2077): 1.03e-18: 96.2: 11.20		MYH11_HUMAN (1730-2541): 1.31e-15: 86: 8.70
+	Hs
		724786 MYH9_HUMAN (1753-2327): 1.1e-12: 76.2: 11.23		DYST_HUMAN (422-2075): 3.73e-15: 84.9: 9.63