HitPredict

Interactor 1: RB3GP (Q15042)
Rab3 GTPase-activating protein catalytic subunit (RAB3 GTPase-activating protein 130 kDa subunit) (Rab3-GAP p130) (Rab3-GAP)
Gene: RAB3GAP1

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 981 Hs			1 1620
+	Hs
		463967 RB3GP_HUMAN (1-981): 0: 1578: 100.00		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		439737 RB3GP_HUMAN (1-981): 0: 1578: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465524 RB3GP_HUMAN (1-981): 0: 1578: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Rn
		98585 F1LP59_RAT (1-981): 0: 1559: 91.81		INSR_RAT (973-1484): 1.46e-112: 392: 32.38
+	Hs
		411959 RB3GP_HUMAN (1-981): 0: 1578: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		541493 RB3GP_HUMAN (1-981): 0: 1578: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07