HitPredict

Interactor 1: Q5XGX4 (Q5XGX4)
E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185)
Gene: rnf185.L

Interactor 2: Q7ZT10 (Q7ZT10)
UV excision repair protein RAD23
Gene: rad23b.S

Species: Xenopus laevis

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	17558393
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-C3HC4
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 189 Xl			1 412
+	Hs
		872296 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		RD23B_HUMAN (1-412): 9.29e-99: 302: 72.82
+	Hs
		872267 HLTF_HUMAN (2-158): 3.35e-29: 115: 18.47		RD23B_HUMAN (1-412): 9.29e-99: 302: 72.82
+	Xl
		1140127 Q5XGX4_XENLA (1-189): 1.24e-64: 198: 100.00		Q6DCM1_XENLA (1-378): 1.37e-43: 161: 12.50
+	Hs
		1292364 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		UBQL1_HUMAN (1-378): 5.03e-48: 174: 12.56
+	Xl
		1140135 Q5XGX4_XENLA (1-189): 1.24e-64: 198: 100.00		Q7SY79_XENLA (1-79): 1.97e-26: 113: 31.65
+	Mm
		476948 RN185_MOUSE (1-189): 1.13e-60: 188: 91.67		UBC_MOUSE (1-102): 2.33e-29: 122: 24.51
+	Hs
		475137 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		UBB_HUMAN (1-79): 7.66e-32: 122: 31.65
+	Dm
		1375478 Q9VXP1_DROME (14-189): 1.18e-59: 189: 57.39		R9PY16_DROME (1-71): 5.33e-26: 108: 33.80
+	Hs
		476198 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		UBC_HUMAN (1-80): 2.34e-26: 113: 31.25
+	Dm
		1215068 Q8IR26_DROME (14-188): 7.47e-53: 171: 52.27		Q9W418_DROME (1-80): 9.64e-27: 113: 32.50
+	Dm
		1215070 Q8IR26_DROME (14-188): 7.47e-53: 171: 52.27		R9PY16_DROME (1-71): 5.33e-26: 108: 33.80
+	Xl
		1140130 Q5XGX4_XENLA (1-189): 1.24e-64: 198: 100.00		Q6GMC1_XENLA (1-75): 2.48e-15: 75: 32.00
+	Xl
		1140133 Q5XGX4_XENLA (1-189): 1.24e-64: 198: 100.00		Q6GQF3_XENLA (1-75): 1.26e-15: 75: 32.00
+	Hs
		924117 RN185_HUMAN (1-189): 1.56e-57: 180: 91.67		RS27A_HUMAN (1-75): 2.48e-15: 75: 32.00
+	Hs
		476274 RNF5_HUMAN (12-154): 3.51e-42: 141: 62.94		UBC_HUMAN (1-80): 2.34e-26: 113: 31.25
+	Hs
		475759 HLTF_HUMAN (2-158): 3.35e-29: 115: 18.47		UBC_HUMAN (1-80): 2.34e-26: 113: 31.25
+	Hs
		475134 TRI11_HUMAN (22-127): 1.15e-25: 104: 24.53		UBB_HUMAN (1-79): 7.66e-32: 122: 31.65
+	Sc
		477459 IRC20_YEAST (23-151): 9.08e-26: 105: 24.03		UBI4P_YEAST (1-79): 8.1e-30: 120: 31.65
+	Hs
		475680 TRI26_HUMAN (22-111): 3.53e-26: 106: 30.77		UBC_HUMAN (1-80): 2.34e-26: 113: 31.25
+	Hs
		476418 TRI39_HUMAN (28-107): 7.62e-25: 102: 27.50		UBC_HUMAN (1-80): 2.34e-26: 113: 31.25