Protein: CLD2
Claudin-2 (SP82)

Gene: CLD2, CLDN2
Organism: Homo sapiens
Interactions: 34
UniProt ID: P57739

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0005923 - bicellular tight junction
GO:0015267 - channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

873279

EMP3
Epithelial membrane protein 3

2

5

High-throughput

0.783

High

207439

LAT
Linker for activation of T-cells family member 1

2

2

High-throughput

0.606

High

884667

MYPR
Myelin proteolipid protein

2

1

High-throughput

0.606

High

884670

BT3A2
Butyrophilin subfamily 3 member A2

2

3

High-throughput

0.606

High

884677

GRM2
Metabotropic glutamate receptor 2

2

1

High-throughput

0.606

High

884689

LPAR3
Lysophosphatidic acid receptor 3

2

6

High-throughput

0.606

High

884691

CLC2D
C-type lectin domain family 2 member D

2

7

High-throughput

0.606

High

884680

I27RA
Interleukin-27 receptor subunit alpha

2

0

High-throughput

0.580

High

67023

CRTP1
Cysteine-rich tail protein 1

2

1

High-throughput

0.553

High

623612

IBP5
Insulin-like growth factor-binding protein 5

2

5

High-throughput

0.553

High

884673

CXCL9
C-X-C motif chemokine 9

2

2

High-throughput

0.553

High

884674

KRA11
Keratin-associated protein 1-1

2

3

High-throughput

0.553

High

884679

F209A
Protein FAM209A

2

2

High-throughput

0.553

High

884682

KRA13
Keratin-associated protein 1-3

2

3

High-throughput

0.553

High

884678

K1H1
Keratin, type I cuticular Ha1

1

2

High-throughput

0.523

High

884681

NT2NA
Notch homolog 2 N-terminal-like protein A

1

2

High-throughput

0.523

High

884685

AP2M1
AP-2 complex subunit mu

1

0

Small-scale

0.513

High

884672

ZO1
Tight junction protein ZO-1

1

20

Small-scale

0.501

High

884686

KR412
Keratin-associated protein 4-12

1

3

High-throughput

0.494

High

884690

ZO2
Tight junction protein ZO-2

1

20

Small-scale

0.481

High

884675

Q08AM2
ADAM33 protein

1

2

High-throughput

0.470

High

321517

AP2A1
AP-2 complex subunit alpha-1

1

1

Small-scale

0.445

High

527373

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

Small-scale

0.445

High

884668

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.439

High

884684

LNX1
E3 ubiquitin-protein ligase LNX

1

7

Small-scale

0.439

High

884687

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

2

High-throughput

0.439

High

884671

CLH1
Clathrin heavy chain 1

1

0

Small-scale

0.426

High

58286

TM218
Transmembrane protein 218

2

0

High-throughput

0.316

High

884683

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

0

High-throughput

0.316

High

884692

TX264
Testis-expressed protein 264

2

0

High-throughput

0.316

High

278252

PIAS2
E3 SUMO-protein ligase PIAS2

1

0

Small-scale

0.251

Low

884669

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.251

Low

884676

SQSTM
Sequestosome-1

1

0

Small-scale

0.249

Low

884688

MLP3B
Microtubule-associated proteins 1A/1B light chain 3B

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024