HitPredict

Interactor 1: ARHG6 (Q5ZLR6)
Rho guanine nucleotide exchange factor 6 (Rac/Cdc42 guanine nucleotide exchange factor 6)
Gene: ARHGEF6

Interactor 2: Q6LC82 (Q6LC82)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (p21-Rac1)
Gene: cRac1A

Species: Gallus gallus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	12686588
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	PH~Ras, Ras~RhoGEF
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 764 Gg			1 192
+	Hs
		925289 ARHG6_HUMAN (1-763): 0: 576: 73.55		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564535 ARHG6_HUMAN (1-763): 0: 576: 73.55		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545388 ARHG6_HUMAN (1-763): 0: 576: 73.55		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		1066050 ARHG6_HUMAN (1-763): 0: 576: 73.55		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892381 ARHG6_HUMAN (1-763): 0: 576: 73.55		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		894026 ARHG6_HUMAN (1-763): 0: 576: 73.55		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		925271 ARHG7_HUMAN (1-706): 8e-159: 482: 54.30		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		564524 ARHG7_HUMAN (1-706): 8e-159: 482: 54.30		RHOQ_HUMAN (4-187): 4.46e-85: 251: 64.67
+	Hs
		545368 ARHG7_HUMAN (1-706): 8e-159: 482: 54.30		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		1049733 ARHG7_HUMAN (1-706): 8e-159: 482: 54.30		RHOJ_HUMAN (2-189): 1.38e-80: 240: 60.64
+	Hs
		892365 ARHG7_HUMAN (1-706): 8e-159: 482: 54.30		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		893997 ARHG7_HUMAN (1-706): 8e-159: 482: 54.30		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		548678 VAV_HUMAN (1-742): 1.78e-129: 407: 17.42		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		548671 VAV_HUMAN (1-742): 1.78e-129: 407: 17.42		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		548672 VAV_HUMAN (1-742): 1.78e-129: 407: 17.42		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		855782 VAV2_HUMAN (1-747): 1.81e-118: 379: 15.72		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		925718 VAV3_HUMAN (1-739): 8.57e-115: 368: 18.81		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		855778 VAV2_HUMAN (1-747): 1.81e-118: 379: 15.72		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		855779 VAV2_HUMAN (1-747): 1.81e-118: 379: 15.72		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		901037 VAV3_HUMAN (1-739): 8.57e-115: 368: 18.81		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98