HitPredict

Interactor 1: EP15R (Q60902)
Epidermal growth factor receptor substrate 15-like 1 (Epidermal growth factor receptor pathway substrate 15-related sequence) (Eps15-rs) (Eps15-related protein) (Eps15R)
Gene: Eps15l1

Interactor 2: ITSN1 (Q9Z0R4)
Intersectin-1 (EH and SH3 domains protein 1)
Gene: ITSN1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	10064583
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016197 - endosomal transport
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 907 Mm			1 1714
+	Hs
		1078923 EP15R_HUMAN (1-860): 2.72e-148: 461: 92.23		ITSN1_HUMAN (1-1714): 0: 873: 93.96
+	Hs
		787920 EPS15_HUMAN (1-905): 5.4e-124: 398: 41.68		ITSN1_HUMAN (1-1714): 0: 873: 93.96
+	Cl
		47357 A0A8I3PJA6_CANLF (1-905): 2.07e-116: 378: 41.85		F1PHV6_CANLF (1-1714): 0: 888: 93.49
+	Mm
		788010 EPS15_MOUSE (1-905): 3.61e-107: 353: 42.86		ITSN1_MOUSE (1-1714): 0: 885: 100.00
+	Hs
		1349279 EP15R_HUMAN (1-860): 2.72e-148: 461: 92.23		ITSN2_HUMAN (1-1713): 0: 728: 55.54
+	Hs
		61738 EP15R_HUMAN (1-860): 2.72e-148: 461: 92.23		A6H8W8_HUMAN (1-1713): 0: 725: 56.22
+	Hs
		787985 EPS15_HUMAN (1-905): 5.4e-124: 398: 41.68		ITSN2_HUMAN (1-1713): 0: 728: 55.54
+	Hs
		61732 EPS15_HUMAN (1-905): 5.4e-124: 398: 41.68		A6H8W8_HUMAN (1-1713): 0: 725: 56.22
+	Rn
		92844 E9PSY8_RAT (9-411): 3.88e-47: 183: 19.01		ITSN1_RAT (1-1714): 0: 874: 97.49
+	Hs
		1078828 ITSN1_HUMAN (2-522): 3.16e-37: 154: 13.52		ITSN1_HUMAN (1-1714): 0: 873: 93.96
+	Hs
		506537 EPS15_HUMAN (1-905): 5.4e-124: 398: 41.68		BCR_HUMAN (720-1675): 2.18e-71: 265: 13.00
+	Mm
		788002 EP15R_MOUSE (1-907): 2.44e-145: 455: 100.00		EPS15_MOUSE (130-720): 2.53e-33: 142: 17.91
+	Hs
		787987 EP15R_HUMAN (1-860): 2.72e-148: 461: 92.23		EPS15_HUMAN (402-571): 1.15e-14: 82: 16.76
+	Mm
		787998 EPS15_MOUSE (1-905): 3.61e-107: 353: 42.86		EPS15_MOUSE (130-720): 2.53e-33: 142: 17.91
+	Hs
		787860 EPS15_HUMAN (1-905): 5.4e-124: 398: 41.68		EPS15_HUMAN (402-571): 1.15e-14: 82: 16.76
+	Rn
		222475 MRCKA_RAT (202-846): 1.35e-37: 155: 7.95		KALRN_RAT (92-1634): 3.08e-75: 281: 11.29
+	Hs
		1078876 ITSN1_HUMAN (2-522): 3.16e-37: 154: 13.52		PREX1_HUMAN (1185-1616): 2.78e-72: 270: 18.89