Interactor 1: PSN2 (Q61144)
Presenilin-2 (PS-2) (EC 3.4.23.-) [Cleaved into: Presenilin-2 NTF subunit; Presenilin-2 CTF subunit]
Gene: Psen2

Interactor 2: APH1A (Q8BVF7)
Gamma-secretase subunit APH-1A (APH-1a) (Aph-1alpha)
Gene: APH1A

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15474363
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Aph-1~Presenilin
Common GO terms GO:0000139 - Golgi membrane
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
and 12 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 448
Mm

1 265
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ Mm
+ Hs
+ At
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024