Interactor 1: ACVL1 (Q61288)
Serine/threonine-protein kinase receptor R3 (SKR3) (EC 2.7.11.30) (Activin receptor-like kinase 1) (ALK-1) (TGF-B superfamily receptor type I) (TSR-I)
Gene: Acvrl1
Interactor 2: NEK8 (Q91ZR4)
Serine/threonine-protein kinase Nek8 (EC 2.7.11.1) (Never in mitosis A-related kinase 8) (NimA-related protein kinase 8)
Gene: NEK8
Species: Mus musculus
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24319055 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PK_Tyr_Ser-Thr~Pkinase, Pkinase~TGF_beta_GS |
| Common GO terms | GO:0005524 - ATP binding GO:0007507 - heart development GO:0016310 - phosphorylation GO:0046872 - metal ion binding |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Last updated: 15 Jul 2024
