Interactor 1: RAGE (Q15109)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: AGER
Interactor 2: TLR9 (Q9NR96)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17417641 |
| Identification Methods | anti tag coimmunoprecipitation, amplified luminescent proximity homogeneous assay |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ig_3~LRR_8 |
| Common GO terms | GO:0001774 - microglial cell activation GO:0005576 - extracellular region GO:0005886 - plasma membrane GO:0016324 - apical plasma membrane GO:0032722 - positive regulation of chemokine production and 4 others more... |
| Homologous interactions | 11 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025