HitPredict

Interactor 1: ATRX (Q61687)
Transcriptional regulator ATRX (EC 3.6.4.12) (ATP-dependent helicase ATRX) (HP1 alpha-interacting protein) (HP1-BP38 protein) (Heterochromatin protein 2) (X-linked nuclear protein)
Gene: ATRX

Interactor 2: MECP2 (Q9Z2D6)
Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2)
Gene: MECP2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 0.60 0.670

The method score is based on:

Property Details
Experiments 17296936, 20159591, 24270455
Identification Methods affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0031490 - chromatin DNA binding
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2476
Mm

1 484
+ Hs
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+ Mm
+ Sp
+ Mm
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+ Hs
+ Hs
+ Dm
+ Dm
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+ Hs
+ Mm
+ Hs
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+ Hs
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+ Hs

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Last updated: 15 Jul 2024