HitPredict

Interactor 1: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	26116754, 34079125, 24255178
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1130 Hs			1 1356
+	Hs
		1256906 LATS2_HUMAN (13-1121): 0: 751: 49.61		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		568742 KAPCA_HUMAN (661-1058): 6.14e-138: 422: 31.59		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		325772 LATS1_HUMAN (1-1130): 0: 934: 100.00		MAGI3_HUMAN (61-1272): 3.28e-32: 139: 10.65
+	Hs
		280011 LATS1_HUMAN (1-1130): 0: 934: 100.00		MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82
+	Hs
		325709 LATS1_HUMAN (1-1130): 0: 934: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		325859 LATS1_HUMAN (1-1130): 0: 934: 100.00		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		325820 LATS1_HUMAN (1-1130): 0: 934: 100.00		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		325703 LATS1_HUMAN (1-1130): 0: 934: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		325729 LATS1_HUMAN (1-1130): 0: 934: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		1137888 MRCKA_HUMAN (694-1047): 2.92e-66: 248: 39.06		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		1232910 LATS2_HUMAN (13-1121): 0: 751: 49.61		LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35
+	Hs
		280078 LATS2_HUMAN (13-1121): 0: 751: 49.61		MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82
+	Hs
		1020225 LATS2_HUMAN (13-1121): 0: 751: 49.61		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		1300675 LATS2_HUMAN (13-1121): 0: 751: 49.61		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		1246440 LATS2_HUMAN (13-1121): 0: 751: 49.61		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		990944 LATS2_HUMAN (13-1121): 0: 751: 49.61		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Dm
		1001628 WARTS_DROME (161-1065): 1.96e-152: 486: 39.48		Q0KHR3_DROME (42-1082): 6.25e-62: 235: 20.76
+	Ce
		88187 WARTS_CAEEL (397-1088): 1.32e-154: 486: 35.43		D3YT29_CAEEL (438-686): 2.81e-30: 131: 21.85
+	Mm
		933108 KAPCB_MOUSE (661-1056): 2.81e-133: 410: 32.25		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		990961 MRCKB_HUMAN (695-1047): 8.47e-63: 236: 38.06		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06