HitPredict

Interactor 1: DLG4 (Q62108)
Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
Gene: DLG4

Interactor 2: AGRB3 (Q80ZF8)
Adhesion G protein-coupled receptor B3 (Brain-specific angiogenesis inhibitor 3)
Gene: Adgrb3

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28671696, 36417873, 36604605
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0051965 - positive regulation of synapse assembly GO:0098794 - postsynapse GO:0098839 - postsynaptic density membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 724 Mm			1 1522
+	Mm
		1112552 DLG4_MOUSE (1-724): 0: 671: 100.00		AGRB1_MOUSE (30-1522): 0: 885: 46.36
+	Hs
		146752 DLG4_HUMAN (1-724): 0: 671: 99.59		AGRB1_HUMAN (30-1522): 0: 841: 46.46
+	Hs
		225263 DLG4_HUMAN (1-724): 0: 671: 99.59		AGRB2_HUMAN (30-1522): 0: 828: 47.17
+	Mm
		1143430 DLG4_MOUSE (1-724): 0: 671: 100.00		AGRB2_MOUSE (30-1522): 0: 816: 47.02
+	Hs
		146753 DLG1_HUMAN (28-724): 0: 576: 72.79		AGRB1_HUMAN (30-1522): 0: 841: 46.46
+	Mm
		1143372 DLG4_MOUSE (1-724): 0: 671: 100.00		AGRL3_MOUSE (506-1469): 0: 634: 19.44
+	Mm
		1143371 DLG4_MOUSE (1-724): 0: 671: 100.00		AGRL1_MOUSE (513-1473): 9.27e-139: 466: 18.77
+	Mm
		1143417 DLG4_MOUSE (1-724): 0: 671: 100.00		AGRA1_MOUSE (856-1378): 1.77e-76: 267: 16.99
+	Hs
		1021530 DLG1_HUMAN (28-724): 0: 576: 72.79		AGRA3_HUMAN (478-1360): 3.05e-94: 336: 16.56
+	Hs
		1021524 DLG1_HUMAN (28-724): 0: 576: 72.79		AGRA1_HUMAN (856-1378): 4.07e-86: 295: 17.38
+	Hs
		1021552 DLG1_HUMAN (28-724): 0: 576: 72.79		AGRA2_HUMAN (475-1340): 8.58e-78: 285: 14.68