HitPredict

Interactor 1: SH3G2 (Q62420)
Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4)
Gene: Sh3gl2

Interactor 2: AMPH (Q7TQF7)
Amphiphysin
Gene: AMPH

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12456676
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	BAR~BAR
Common GO terms	GO:0048488 - synaptic vesicle endocytosis GO:0098684 - photoreceptor ribbon synapse GO:0098793 - presynapse GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 352 Mm			1 686
+	Mm
		1143928 SH3G3_MOUSE (1-351): 1.51e-90: 276: 64.67		AMPH_MOUSE (1-686): 7.42e-129: 398: 100.00
+	Rn
		139969 SH3G2_RAT (1-352): 7.14e-93: 283: 99.43		AMPH_RAT (1-686): 1.11e-113: 359: 92.14
+	Hs
		827760 SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86		AMPH_HUMAN (1-686): 2.96e-112: 355: 82.16
+	Mm
		1186721 SHLB1_MOUSE (10-347): 1.46e-72: 231: 24.79		AMPH_MOUSE (1-686): 7.42e-129: 398: 100.00
+	Hs
		203249 SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86		SYNJ1_HUMAN (38-650): 2.06e-38: 155: 12.62
+	Rn
		192354 SH3G2_RAT (1-352): 7.14e-93: 283: 99.43		SYNJ1_RAT (38-650): 1.74e-37: 152: 11.57
+	Mm
		88459 SH3G2_MOUSE (1-352): 6.2e-93: 283: 100.00		D3Z656_MOUSE (38-650): 1.79e-36: 149: 12.01
+	Mm
		88460 SH3G3_MOUSE (1-351): 1.51e-90: 276: 64.67		D3Z656_MOUSE (38-650): 1.79e-36: 149: 12.01
+	Rn
		192356 SH3G3_RAT (1-352): 2.35e-87: 268: 64.77		SYNJ1_RAT (38-650): 1.74e-37: 152: 11.57
+	Hs
		203248 SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29		SYNJ1_HUMAN (38-650): 2.06e-38: 155: 12.62
+	Rn
		193638 SH3G1_RAT (1-352): 6.16e-84: 260: 69.02		SYNJ1_RAT (38-650): 1.74e-37: 152: 11.57
+	Hs
		1307440 SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86		ASAP1_HUMAN (271-682): 5.08e-27: 119: 12.53
+	Mm
		139037 SH3G2_MOUSE (1-352): 6.2e-93: 283: 100.00		BIN1_MOUSE (417-686): 1.28e-26: 116: 24.54
+	Mm
		139038 SH3G3_MOUSE (1-351): 1.51e-90: 276: 64.67		BIN1_MOUSE (417-686): 1.28e-26: 116: 24.54
+	Mm
		101448 SH3G1_MOUSE (1-352): 5.02e-84: 261: 68.48		F8VPR5_MOUSE (107-613): 2.6e-30: 130: 12.52
+	Hs
		1270776 SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29		CBP_HUMAN (107-613): 4.19e-28: 123: 13.03
+	Hs
		1052272 SRC8_HUMAN (46-348): 5.2e-46: 166: 14.10		CTTB2_HUMAN (43-640): 4.71e-47: 182: 11.89
+	Mm
		139046 SHLB1_MOUSE (10-347): 1.46e-72: 231: 24.79		BIN1_MOUSE (417-686): 1.28e-26: 116: 24.54
+	Hs
		1264828 SHLB1_HUMAN (10-347): 5.91e-73: 232: 24.79		TITIN_HUMAN (133-559): 2.19e-24: 111: 13.43
+	Hs
		998698 SRC8_HUMAN (46-348): 5.2e-46: 166: 14.10		EP300_HUMAN (107-613): 6.64e-31: 132: 11.92