HitPredict

Interactor 1: SH3G2 (Q62420)
Endophilin-A1 (Endophilin-1) (SH3 domain protein 2A) (SH3 domain-containing GRB2-like protein 2) (SH3p4)
Gene: Sh3gl2

Interactor 2: PDC6I (Q9WU78)
Programmed cell death 6-interacting protein (ALG-2-interacting protein 1) (ALG-2-interacting protein X) (E2F1-inducible protein) (Eig2)
Gene: Pdcd6ip

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	12034747
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 352 Mm			1 869
+	Hs
		1260386 SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Hs
		1260385 SH3G1_HUMAN (1-352): 4.31e-85: 263: 69.29		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Mm
		1143918 SH3G1_MOUSE (1-352): 5.02e-84: 261: 68.48		PDC6I_MOUSE (1-869): 0: 773: 100.00
+	Hs
		1078881 ITSN1_HUMAN (239-346): 9.71e-13: 71.5: 20.87		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Hs
		1191850 SH3R1_HUMAN (283-346): 1.19e-12: 70.9: 44.12		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Hs
		924726 GRB2_HUMAN (295-351): 1.18e-12: 68.2: 43.10		PDC6I_HUMAN (1-869): 0: 787: 94.36
+	Ce
		70028 SH3GH_CAEEL (1-350): 5.37e-67: 217: 43.46		ALXA_CAEEL (4-834): 0: 626: 37.37
+	Mm
		1141174 GRB2_MOUSE (295-351): 1.33e-12: 68.2: 43.10		PDC6I_MOUSE (1-869): 0: 773: 100.00
+	Hs
		1307434 SH3G2_HUMAN (1-352): 3.65e-93: 283: 98.86		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Dm
		1180080 Q7K4D1_DROME (250-351): 1.1e-19: 92.5: 33.33		Q9VB05_DROME (1-869): 0: 646: 40.85
+	Dm
		1342129 Q9NHP2_DROME (250-351): 1.09e-19: 92.5: 33.33		Q9VB05_DROME (1-869): 0: 646: 40.85
+	Ce
		666203 SEM5_CAEEL (275-344): 5.46e-20: 89: 44.29		ALXA_CAEEL (4-834): 0: 626: 37.37
+	Hs
		1078907 ITSN1_HUMAN (239-346): 9.71e-13: 71.5: 20.87		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Hs
		924858 GRB2_HUMAN (295-351): 1.18e-12: 68.2: 43.10		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Hs
		1126375 SH319_HUMAN (296-347): 4.06e-10: 63.2: 55.77		PTN23_HUMAN (3-869): 1.18e-168: 533: 23.93
+	Dm
		993211 GRAP_DROME (296-344): 1.72e-10: 62: 51.02		Q9VUH6_DROME (4-866): 7.61e-144: 468: 21.43
+	Mm
		101448 SH3G1_MOUSE (1-352): 5.02e-84: 261: 68.48		F8VPR5_MOUSE (632-866): 1.16e-25: 116: 16.91
+	Hs
		1307452 SH3G3_HUMAN (1-352): 7.71e-91: 277: 65.34		WDR33_HUMAN (671-867): 4.66e-10: 65.7: 13.33
+	Ce
		70017 SH3GH_CAEEL (1-350): 5.37e-67: 217: 43.46		G5EBN5_CAEEL (433-867): 3.02e-10: 66.5: 12.73
+	Hs
		159946 GRB2_HUMAN (295-351): 1.18e-12: 68.2: 43.10		HGS_HUMAN (550-863): 3.74e-27: 120: 18.10