Interactor 1: IPYR (Q15181)
Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)
Gene: PPA1

Interactor 2: IPYR2 (Q9H2U2)
Inorganic pyrophosphatase 2, mitochondrial (EC 3.6.1.1) (Pyrophosphatase SID6-306) (Pyrophosphate phospho-hydrolase 2) (PPase 2)
Gene: PPA2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 28524877
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pyrophosphatase~Pyrophosphatase
Common GO terms GO:0000287 - magnesium ion binding
GO:0004427 - inorganic diphosphate phosphatase activity
GO:0006796 - phosphate-containing compound metabolic process
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 289
Hs

1 334
+ Mm
+ Sc
+ Sc
+ At
+ Hp
+ Ec

Service provided by Combinatics, Japan

Last updated: 11Aug2025