Protein: IPYR
Inorganic pyrophosphatase (EC 3.6.1.1) (Pyrophosphate phospho-hydrolase) (PPase)

Gene: IPYR, ppa
Organism: Escherichia coli K-12
Interactions: 45
UniProt ID: P0A7A9

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0004427 - inorganic diphosphate phosphatase activity
GO:0005829 - cytosol
GO:0006796 - phosphate-containing compound metabolic process
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

492052

IPYR
Inorganic pyrophosphatase

1

6

High-throughput

0.618

High

492070

RRAB
Regulator of ribonuclease activity B

2

0

High-throughput

0.576

High

492072

SECB
Protein-export protein SecB

2

0

High-throughput

0.576

High

492075

KATG
Catalase-peroxidase

2

0

High-throughput

0.576

High

492078

ACPT
4'-phosphopantetheinyl transferase AcpT

2

0

High-throughput

0.576

High

492083

RL4
Large ribosomal subunit protein uL4

2

0

High-throughput

0.576

High

491798

MSRA
Peptide methionine sulfoxide reductase MsrA

1

0

High-throughput

0.513

High

492053

RL10
Large ribosomal subunit protein uL10

1

0

High-throughput

0.513

High

492068

HEMG
Protoporphyrinogen IX dehydrogenase [quinone]

1

0

High-throughput

0.513

High

492076

RHLE
ATP-dependent RNA helicase RhlE

1

0

High-throughput

0.513

High

490388

DADA
D-amino acid dehydrogenase

1

1

High-throughput

0.489

High

489486

CH60
Chaperonin GroEL

1

1

High-throughput

0.484

High

490994

DNAK
Chaperone protein DnaK

1

2

High-throughput

0.484

High

492057

RS10
Small ribosomal subunit protein uS10

1

1

High-throughput

0.484

High

492059

RS2
Small ribosomal subunit protein uS2

1

1

High-throughput

0.484

High

492060

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.484

High

492061

RS5
Small ribosomal subunit protein uS5

1

1

High-throughput

0.484

High

492066

RL13
Large ribosomal subunit protein uL13

1

2

High-throughput

0.484

High

492073

EFTU1
Elongation factor Tu 1

1

4

High-throughput

0.484

High

492082

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.484

High

382635

RS7
Small ribosomal subunit protein uS7

1

0

High-throughput

0.464

High

492054

RL19
Large ribosomal subunit protein bL19

1

0

High-throughput

0.464

High

492055

RL28
Large ribosomal subunit protein bL28

1

0

High-throughput

0.464

High

492056

RL9
Large ribosomal subunit protein bL9

1

0

High-throughput

0.464

High

492058

RS20
Small ribosomal subunit protein bS20

1

0

High-throughput

0.464

High

492062

RS8
Small ribosomal subunit protein uS8

1

0

High-throughput

0.464

High

492063

TIG
Trigger factor

1

0

High-throughput

0.464

High

492064

DPO3B
Beta sliding clamp

1

0

High-throughput

0.464

High

492065

SLYD
FKBP-type peptidyl-prolyl cis-trans isomerase SlyD

1

0

High-throughput

0.464

High

492069

RL14
Large ribosomal subunit protein uL14

1

0

High-throughput

0.464

High

492084

RL22
Large ribosomal subunit protein uL22

1

0

High-throughput

0.464

High

492085

HLDD
ADP-L-glycero-D-manno-heptose-6-epimerase

1

0

High-throughput

0.464

High

420138

KDSB
3-deoxy-manno-octulosonate cytidylyltransferase

1

0

High-throughput

0.458

High

460390

SYL
Leucine--tRNA ligase

1

0

High-throughput

0.458

High

492067

KDTA
3-deoxy-D-manno-octulosonic acid transferase

1

0

High-throughput

0.458

High

492074

EFTU2
Elongation factor Tu 2

1

4

High-throughput

0.407

High

492077

ACTP
Cation/acetate symporter ActP

2

0

High-throughput

0.313

High

492086

YBGQ
Uncharacterized outer membrane usher protein YbgQ

2

0

High-throughput

0.313

High

492087

ATOD
Acetate CoA-transferase subunit alpha

2

0

High-throughput

0.313

High

492080

DEGQ
Periplasmic pH-dependent serine endoprotease DegQ

1

0

High-throughput

0.279

Low

492071

RS14
Small ribosomal subunit protein uS14

1

0

High-throughput

0.253

Low

490366

COAD
Phosphopantetheine adenylyltransferase

1

0

High-throughput

0.249

Low

492079

WBBK
Putative glycosyltransferase WbbK

1

0

High-throughput

0.249

Low

492081

YHDP
Intermembrane phospholipid transporter YhdP

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025