Interactor 1: PTPRZ (Q62656)
Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) (EC 3.1.3.48) (3F8 chondroitin sulfate proteoglycan) (3H1 keratan sulfate proteoglycan) (Phosphacan)
Gene: Ptprz1
Interactor 2: ERBB4 (Q62956)
Receptor tyrosine-protein kinase erbB-4 (EC 2.7.10.1) (Proto-oncogene-like protein c-ErbB-4) [Cleaved into: ERBB4 intracellular domain (4ICD) (E4ICD) (s80HER4)]
Gene: ERBB4
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 17646177 |
| Identification Methods | affinity chromatography technology, enzymatic study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Furin-like~fn3, PK_Tyr_Ser-Thr~fn3, Recep_L_domain~fn3, PK_Tyr_Ser-Thr~Y_phosphatase |
| Common GO terms | GO:0005886 - plasma membrane GO:0008285 - negative regulation of cell population proliferation GO:0030335 - positive regulation of cell migration GO:0030425 - dendrite GO:0043025 - neuronal cell body and 3 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
