HitPredict

Interactor 1: M9PCJ7 (M9PCJ7)
Utx histone demethylase, isoform E (EC 1.14.11.68)
Gene: Utx

Interactor 2: RBBP5 (Q9VPH8)
Retinoblastoma-binding protein 5 homolog
Gene: RBBP5

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21875999
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0044666 - MLL3/4 complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 934 Dm			1 489
+	Dm
		114491 M9PCJ7_DROME (1-934): 0: 1001: 100.00		WDS_DROME (96-404): 2.6e-64: 214: 11.56
+	Mm
		1129461 KDM6B_MOUSE (446-924): 0: 670: 58.88		RBBP5_MOUSE (1-489): 4.91e-109: 335: 65.59
+	Hs
		165853 KDM6B_HUMAN (446-924): 0: 664: 58.88		RBBP5_HUMAN (1-489): 4.31e-109: 335: 65.59
+	Hs
		165835 KDM6B_HUMAN (446-924): 0: 664: 58.88		WDR5_HUMAN (234-399): 7.43e-22: 98.1: 12.72
+	Ce
		1089275 JMJ31_CAEEL (465-922): 0: 559: 28.22		WDR51_CAEEL (97-403): 1.77e-59: 202: 11.01
+	Hs
		672838 CDC27_HUMAN (1-333): 1.42e-50: 193: 11.99		RBBP5_HUMAN (1-489): 4.31e-109: 335: 65.59
+	Hs
		150102 UTY_HUMAN (2-494): 9.61e-29: 126: 11.86		RBBP5_HUMAN (1-489): 4.31e-109: 335: 65.59
+	Hs
		174908 OGT1_HUMAN (108-411): 1.33e-27: 122: 13.77		RBBP5_HUMAN (1-489): 4.31e-109: 335: 65.59
+	Hs
		183118 KDM6A_HUMAN (6-700): 6.93e-22: 104: 12.99		RBBP5_HUMAN (1-489): 4.31e-109: 335: 65.59
+	Hs
		672800 CDC27_HUMAN (1-333): 1.42e-50: 193: 11.99		WDR5_HUMAN (234-399): 7.43e-22: 98.1: 12.72
+	Sp
		224208 CYC8_SCHPO (49-610): 1.57e-24: 112: 12.50		TUP12_SCHPO (16-323): 2.08e-37: 146: 16.72
+	Hs
		175177 OGT1_HUMAN (108-411): 1.33e-27: 122: 13.77		TBL1R_HUMAN (106-338): 2.8e-31: 128: 12.10
+	Ca
		483035 Q5ADP3_CANAL (101-371): 6.01e-23: 107: 14.80		TUP1_CANAL (188-417): 7.96e-30: 123: 13.01
+	Sp
		224207 CYC8_SCHPO (49-610): 1.57e-24: 112: 12.50		TUP11_SCHPO (175-370): 3.85e-26: 113: 13.20
+	Hs
		150096 UTY_HUMAN (2-494): 9.61e-29: 126: 11.86		WDR5_HUMAN (234-399): 7.43e-22: 98.1: 12.72
+	Hs
		183146 KDM6A_HUMAN (6-700): 6.93e-22: 104: 12.99		FBXW7_HUMAN (181-390): 5.18e-28: 119: 10.23
+	Hs
		174768 OGT1_HUMAN (108-411): 1.33e-27: 122: 13.77		WDR5_HUMAN (234-399): 7.43e-22: 98.1: 12.72
+	Hs
		684552 STIP1_HUMAN (27-397): 1.05e-09: 64.1: 9.86		COPA_HUMAN (143-398): 2.06e-37: 148: 14.79
+	Hs
		183095 KDM6A_HUMAN (6-700): 6.93e-22: 104: 12.99		WDR5_HUMAN (234-399): 7.43e-22: 98.1: 12.72
+	Hs
		99745 F5H5V6_HUMAN (6-487): 1.39e-20: 100: 12.32		WDR5_HUMAN (234-399): 7.43e-22: 98.1: 12.72