HitPredict

Interactor 1: HS105 (Q66HA8)
Heat shock protein 105 kDa (Heat shock 110 kDa protein)
Gene: Hsph1

Interactor 2: GRB7 (Q9QZC5)
Growth factor receptor-bound protein 7 (Epidermal growth factor receptor GRB-7) (GRB7 adapter protein)
Gene: GRB7

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32360748
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Rn			1 535
+	Hs
		1031696 HS105_HUMAN (1-858): 0: 973: 92.20		GRB10_HUMAN (1-535): 0: 555: 52.88
+	Hs
		320849 HS74L_HUMAN (1-856): 0: 926: 56.89		GRB10_HUMAN (1-535): 0: 555: 52.88
+	Hs
		714211 HSP74_HUMAN (1-858): 0: 903: 59.30		GRB10_HUMAN (1-535): 0: 555: 52.88
+	Hs
		855818 HS105_HUMAN (1-858): 0: 973: 92.20		VAV2_HUMAN (85-529): 4.68e-77: 261: 13.68
+	Hs
		850758 HS105_HUMAN (1-858): 0: 973: 92.20		BMX_HUMAN (223-534): 2.07e-49: 182: 16.39
+	Hs
		412286 HS105_HUMAN (1-858): 0: 973: 92.20		FYN_HUMAN (372-532): 1.7e-45: 169: 19.05
+	Hs
		523090 HS105_HUMAN (1-858): 0: 973: 92.20		SRC_HUMAN (360-531): 2.51e-41: 158: 22.91
+	Hs
		782813 HS105_HUMAN (1-858): 0: 973: 92.20		CSK_HUMAN (397-528): 1.44e-29: 122: 28.26
+	Hs
		412053 HSP74_HUMAN (1-858): 0: 903: 59.30		FYN_HUMAN (372-532): 1.7e-45: 169: 19.05
+	Hs
		522818 HSP74_HUMAN (1-858): 0: 903: 59.30		SRC_HUMAN (360-531): 2.51e-41: 158: 22.91
+	Hs
		714124 HSP74_HUMAN (1-858): 0: 903: 59.30		CSK_HUMAN (397-528): 1.44e-29: 122: 28.26
+	Rn
		926185 HSP7C_RAT (591-710): 4.19e-31: 132: 16.39		GRB7_RAT (1-535): 0: 598: 100.00
+	Hs
		924985 HYOU1_HUMAN (1-807): 8.84e-81: 282: 27.41		GRB2_HUMAN (400-516): 2.34e-14: 74: 27.35
+	Hs
		411570 HSP7C_HUMAN (591-710): 2.45e-31: 132: 16.39		LCK_HUMAN (320-530): 7.02e-46: 170: 20.87
+	Hs
		411965 HSP7C_HUMAN (591-710): 2.45e-31: 132: 16.39		FYN_HUMAN (372-532): 1.7e-45: 169: 19.05
+	Hs
		433227 HSP7C_HUMAN (591-710): 2.45e-31: 132: 16.39		YES_HUMAN (372-533): 8.44e-45: 167: 20.12
+	Hs
		442767 HSP7C_HUMAN (591-710): 2.45e-31: 132: 16.39		HCK_HUMAN (379-530): 1.22e-44: 166: 21.52
+	Hs
		503340 HSP7C_HUMAN (591-710): 2.45e-31: 132: 16.39		SRC_HUMAN (360-531): 2.51e-41: 158: 22.91
+	Hs
		503596 HSP7C_HUMAN (591-710): 2.45e-31: 132: 16.39		CSK_HUMAN (397-528): 1.44e-29: 122: 28.26
+	Hs
		713938 HS71L_HUMAN (600-718): 2.72e-31: 132: 20.00		GRB2_HUMAN (400-516): 2.34e-14: 74: 27.35