Protein: AROS
Active regulator of SIRT1 (40S ribosomal protein S19-binding protein 1) (RPS19-binding protein 1) (S19BP)

Gene: AROS, RPS19BP1
Organism: Homo sapiens
Interactions: 99
UniProt ID: Q86WX3

Gene Ontology (top 5):
GO:0003723 - RNA binding
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0019899 - enzyme binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1292963

SIR1
NAD-dependent protein deacetylase sirtuin-1

6

0

Small-scale

0.704

High

1290271

KBTB6
Kelch repeat and BTB domain-containing protein 6

2

1

High-throughput

0.628

High

1292961

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

1

High-throughput

0.628

High

950564

KR108
Keratin-associated protein 10-8

2

3

High-throughput

0.606

High

1059685

KRA11
Keratin-associated protein 1-1

2

3

High-throughput

0.606

High

1146017

K1H1
Keratin, type I cuticular Ha1

2

1

High-throughput

0.606

High

1292956

KRA13
Keratin-associated protein 1-3

2

3

High-throughput

0.606

High

133368

DCTN6
Dynactin subunit 6

2

0

High-throughput

0.602

High

298196

DCTN3
Dynactin subunit 3

2

0

High-throughput

0.602

High

1123700

DCTN1
Dynactin subunit 1

2

0

High-throughput

0.602

High

1292977

ARP10
Actin-related protein 10

2

0

High-throughput

0.602

High

839580

HUTH
Histidine ammonia-lyase

2

0

High-throughput

0.585

High

1292957

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

0

High-throughput

0.549

High

1023024

FGD1
FYVE, RhoGEF and PH domain-containing protein 1

2

0

High-throughput

0.547

High

276602

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

1

High-throughput

0.536

High

652348

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

1

High-throughput

0.536

High

713410

SPB3
Serpin B3

1

1

High-throughput

0.536

High

1097400

CBX3
Chromobox protein homolog 3

1

1

High-throughput

0.536

High

1292969

LOXE3
Hydroperoxide isomerase ALOXE3

1

1

High-throughput

0.536

High

564012

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.513

High

729587

CASPE
Caspase-14

1

0

High-throughput

0.513

High

837239

ACTY
Beta-centractin

1

0

High-throughput

0.513

High

1110644

DCTN2
Dynactin subunit 2

1

0

High-throughput

0.513

High

1118228

BLMH
Bleomycin hydrolase

1

0

High-throughput

0.513

High

1214071

KIF24
Kinesin-like protein KIF24

1

0

High-throughput

0.513

High

1256955

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

1292966

CPNS2
Calpain small subunit 2

1

0

High-throughput

0.513

High

1292976

RPC5
DNA-directed RNA polymerase III subunit RPC5

1

0

High-throughput

0.513

High

1292979

TRM7
tRNA

1

0

High-throughput

0.513

High

1292982

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.513

High

289266

SPB7
Serpin B7

1

2

High-throughput

0.489

High

1062257

TGM3
Protein-glutamine gamma-glutamyltransferase E

1

1

High-throughput

0.489

High

1292958

SPA12
Serpin A12

1

2

High-throughput

0.489

High

300405

KRT34
Keratin, type I cuticular Ha4

1

1

High-throughput

0.481

High

949923

KR103
Keratin-associated protein 10-3

1

3

High-throughput

0.481

High

1292985

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

254383

CC14B
Dual specificity protein phosphatase CDC14B

1

3

High-throughput

0.479

High

262535

MCE1
mRNA-capping enzyme

1

3

High-throughput

0.479

High

372467

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

406351

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

711147

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

1

High-throughput

0.479

High

767066

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

1

High-throughput

0.479

High

1014149

CBX1
Chromobox protein homolog 1

1

1

High-throughput

0.479

High

1091821

TP4A2
Protein tyrosine phosphatase type IVA 2

1

2

High-throughput

0.479

High

1292984

PTN22
Tyrosine-protein phosphatase non-receptor type 22

1

1

High-throughput

0.479

High

517052

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.470

High

892693

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

315748

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

319883

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

401085

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

404184

GCR
Glucocorticoid receptor

1

0

High-throughput

0.458

High

643921

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

937809

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

970728

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1094782

CAF1B
Chromatin assembly factor 1 subunit B

1

0

High-throughput

0.458

High

1100082

TIF1B
Transcription intermediary factor 1-beta

1

0

High-throughput

0.458

High

1112410

MTMR2
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR2

1

0

High-throughput

0.458

High

1132803

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1137827

TNIP1
TNFAIP3-interacting protein 1

1

0

High-throughput

0.458

High

1155518

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1212412

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.458

High

1240746

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.458

High

1277173

POGZ
Pogo transposable element with ZNF domain

1

0

High-throughput

0.458

High

1292964

NSL1
Kinetochore-associated protein NSL1 homolog

1

0

High-throughput

0.458

High

1292965

CHAP1
Chromosome alignment-maintaining phosphoprotein 1

1

0

High-throughput

0.458

High

1292967

RING2
E3 ubiquitin-protein ligase RING2

1

0

High-throughput

0.458

High

1292968

TBX5
T-box transcription factor TBX5

1

0

High-throughput

0.458

High

1292970

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.458

High

1292971

RGAP1
Rac GTPase-activating protein 1

1

0

Small-scale

0.458

High

1292973

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.458

High

1292975

RC3H2
Roquin-2

1

0

High-throughput

0.458

High

1292978

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

1292980

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1292983

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.458

High

809709

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.445

High

1277297

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

75687

B3KVV6
cDNA FLJ41607 fis, clone CTONG3001370, highly similar to Homo sapiens alpha-2-macroglobulin-like 1

1

1

High-throughput

0.437

High

1292962

TP4A1
Protein tyrosine phosphatase type IVA 1

1

3

High-throughput

0.437

High

344236

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

414138

P53
Cellular tumor antigen p53

1

0

Small-scale

0.426

High

1198590

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.426

High

69512

A2ML1
Alpha-2-macroglobulin-like protein 1

1

1

High-throughput

0.407

High

70323

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

1205860

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

0

High-throughput

0.316

High

1250253

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

278691

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

0

High-throughput

0.279

Low

423800

APOD
Apolipoprotein D

1

0

High-throughput

0.279

Low

671820

ZA2G
Zinc-alpha-2-glycoprotein

1

0

High-throughput

0.279

Low

892114

KLK7
Kallikrein-7

1

0

High-throughput

0.279

Low

1200989

ACTBL
Beta-actin-like protein 2

1

0

High-throughput

0.279

Low

1204004

FILA2
Filaggrin-2

1

0

High-throughput

0.279

Low

1292960

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

1292981

CBPA4
Carboxypeptidase A4

1

0

High-throughput

0.279

Low

567

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

1094700

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.249

Low

1126116

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

1292959

CC71L
Coiled-coil domain-containing protein 71L

1

0

High-throughput

0.249

Low

1292972

ADNP
Activity-dependent neuroprotector homeobox protein

1

0

High-throughput

0.249

Low

1292974

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025