HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: HOME1 (Q86YM7)
Homer protein homolog 1 (Homer-1)
Gene: HOMER1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 354
+	Hs
		1146932 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		EVL_HUMAN (1-160): 1.25e-28: 116: 21.82
+	Hs
		840499 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		VASP_HUMAN (1-146): 3.19e-28: 115: 22.36
+	Hs
		1113790 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		GRDN_HUMAN (158-347): 6.51e-26: 111: 22.28
+	Hs
		1146919 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		EP15R_HUMAN (65-303): 4.1e-18: 87.8: 11.94
+	Hs
		1146502 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		MRCKG_HUMAN (183-349): 3.69e-10: 63.5: 17.24
+	Hs
		1146648 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		DLG5_HUMAN (107-349): 5.1e-10: 63.1: 13.81
+	Hs
		1132650 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		FKB15_HUMAN (72-353): 8.97e-09: 59.3: 14.34
+	Hs
		921592 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		GRDN_HUMAN (158-347): 6.51e-26: 111: 22.28
+	Hs
		793015 LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98		DLG5_HUMAN (107-349): 5.1e-10: 63.1: 13.81
+	Hs
		551632 LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98		DESP_HUMAN (95-342): 9.29e-09: 59.3: 12.30
+	Mm
		936833 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		VASP_MOUSE (1-146): 6.58e-31: 122: 21.66
+	Mm
		936782 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		EVL_MOUSE (1-153): 1.5e-27: 113: 21.52
+	Hs
		551854 NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34		DESP_HUMAN (95-342): 9.29e-09: 59.3: 12.30
+	Mm
		1160662 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		FKB15_MOUSE (101-354): 1.82e-24: 107: 16.92
+	Hs
		551659 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		DESP_HUMAN (95-342): 9.29e-09: 59.3: 12.30
+	Mm
		1141844 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		EP15R_MOUSE (65-303): 7.91e-15: 77.8: 10.82
+	Hs
		551766 WDR5B_HUMAN (165-393): 1.21e-20: 95.1: 11.72		DESP_HUMAN (95-342): 9.29e-09: 59.3: 12.30
+	Hs
		551655 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		DESP_HUMAN (95-342): 9.29e-09: 59.3: 12.30
+	Hs
		1132663 POC1A_HUMAN (188-352): 4.31e-16: 82.8: 13.98		FKB15_HUMAN (72-353): 8.97e-09: 59.3: 14.34