Protein: VP37A
Vacuolar protein sorting-associated protein 37A (hVps37A) (ESCRT-I complex subunit VPS37A) (Hepatocellular carcinoma-related protein 1)

Gene: VP37A, VPS37A
Organism: Homo sapiens
Interactions: 131
UniProt ID: Q8NEZ2

Gene Ontology (top 5):
GO:0000813 - ESCRT I complex
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
GO:0005829 - cytosol
GO:0006612 - protein targeting to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1338211

TS101
Tumor susceptibility gene 101 protein

13

9

Small-scale

0.983

High

1338237

VPS28
Vacuolar protein sorting-associated protein 28 homolog

7

8

Small-scale

0.969

High

1338233

UBAP1
Ubiquitin-associated protein 1

6

1

Small-scale

0.730

High

1338207

MB12A
Multivesicular body subunit 12A

1

7

Small-scale

0.618

High

1338224

MB12B
Multivesicular body subunit 12B

1

7

Small-scale

0.618

High

1338196

TNIP2
TNFAIP3-interacting protein 2

2

3

High-throughput

0.611

High

508295

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

4

High-throughput

0.602

High

638215

S1PR1
Sphingosine 1-phosphate receptor 1

1

1

High-throughput

0.536

High

921963

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

1311444

TRI42
Tripartite motif-containing protein 42

1

2

High-throughput

0.523

High

167330

KLF11
Krueppel-like factor 11

1

1

High-throughput

0.515

High

216757

HTRA2
Serine protease HTRA2, mitochondrial

1

1

High-throughput

0.515

High

272840

PHF2
Lysine-specific demethylase PHF2

1

0

High-throughput

0.513

High

1338209

RBM14
RNA-binding protein 14

1

0

High-throughput

0.513

High

1338241

HDGR3
Hepatoma-derived growth factor-related protein 3

1

0

High-throughput

0.513

High

246777

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.508

High

422648

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

374784

RASH
GTPase HRas

1

0

High-throughput

0.493

High

442409

GELS
Gelsolin

1

0

High-throughput

0.493

High

767268

MERL
Merlin

1

0

High-throughput

0.493

High

843784

HD
Huntingtin

1

0

High-throughput

0.493

High

927069

ATX3
Ataxin-3

1

0

High-throughput

0.493

High

954549

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

1096108

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.493

High

1279648

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.493

High

1338199

GDAP1
Ganglioside-induced differentiation-associated protein 1

1

0

High-throughput

0.493

High

169664

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

7

Small-scale

0.479

High

173096

XPO1
Exportin-1

1

1

High-throughput

0.479

High

242329

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

714280

PML
Protein PML

1

1

High-throughput

0.479

High

1277467

ZFY16
Zinc finger FYVE domain-containing protein 16

1

3

Small-scale

0.479

High

1338206

OPTN
Optineurin

1

1

High-throughput

0.479

High

1338236

UBQL2
Ubiquilin-2

1

3

High-throughput

0.479

High

109469

G5E9A7
DM1 locus, WD repeat containing

1

1

High-throughput

0.470

High

1292907

Q86WV8
TSC complex subunit 1

1

2

High-throughput

0.470

High

48707

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

296530

STAM2
Signal transducing adapter molecule 2

1

9

High-throughput

0.445

High

462521

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

1

High-throughput

0.445

High

567032

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.445

High

697961

CALR
Calreticulin

1

1

High-throughput

0.445

High

773574

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.445

High

987124

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

1

High-throughput

0.445

High

1146584

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.445

High

1258781

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.445

High

1316260

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

1333904

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.445

High

1338208

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

1338227

PDLI7
PDZ and LIM domain protein 7

1

2

High-throughput

0.445

High

1338234

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

1338235

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

1338243

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

1338203

TRI63
E3 ubiquitin-protein ligase TRIM63

1

1

High-throughput

0.439

High

1338217

TRI55
Tripartite motif-containing protein 55

1

1

High-throughput

0.439

High

60378

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

158264

COPE
Coatomer subunit epsilon

1

0

High-throughput

0.426

High

211824

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

213629

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

360045

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

535310

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

873273

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

876938

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

883117

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

904014

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

921724

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

964036

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

1009859

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

1097008

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

1131326

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

1139227

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

1139347

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1248632

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

1338200

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.426

High

1338204

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.426

High

1338205

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

1338210

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1338218

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

1338219

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

1338220

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.426

High

1338221

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1338242

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

104353

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.407

High

275538

RTN2
Reticulon-2

1

2

High-throughput

0.407

High

328957

RTN3
Reticulon-3

1

2

High-throughput

0.407

High

333107

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.407

High

698912

CALX
Calnexin

1

1

High-throughput

0.407

High

888928

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.407

High

1199218

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.407

High

1338197

ATLA2
Atlastin-2

1

2

High-throughput

0.407

High

1338201

ATLA1
Atlastin-1

1

2

High-throughput

0.407

High

1338214

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.407

High

1338222

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.407

High

1338226

RTN4
Reticulon-4

1

2

High-throughput

0.407

High

1338238

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.407

High

1338239

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.407

High

1327826

ARRD1
Arrestin domain-containing protein 1

3

0

High-throughput

0.347

High

246059

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.268

Low

301578

WFS1
Wolframin

1

0

High-throughput

0.268

Low

650307

FGFR3
Fibroblast growth factor receptor 3

1

0

High-throughput

0.268

Low

705474

GRN
Progranulin

1

0

High-throughput

0.268

Low

1338202

JPH3
Junctophilin-3

1

0

High-throughput

0.268

Low

1338216

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

1338240

RNF11
RING finger protein 11

1

0

High-throughput

0.268

Low

106307

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

377661

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

1276504

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1327088

FBXL6
F-box/LRR-repeat protein 6

1

0

High-throughput

0.249

Low

1338223

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

Small-scale

0.249

Low

50627

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

215607

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.232

Low

283313

ERLN1
Erlin-1

1

0

High-throughput

0.232

Low

319002

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.232

Low

903740

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

1015067

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.232

Low

1027093

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

1136282

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.232

Low

1145626

RCN1
Reticulocalbin-1

1

0

High-throughput

0.232

Low

1147800

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.232

Low

1152823

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.232

Low

1327898

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.232

Low

1330315

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

1337601

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

1338198

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.232

Low

1338212

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

1338213

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.232

Low

1338215

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

1338225

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

1338228

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

1338229

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

1338230

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

1338231

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low

1338232

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025