HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: ARG28 (Q8N1W1)
Rho guanine nucleotide exchange factor 28 (190 kDa guanine nucleotide exchange factor) (p190-RhoGEF) (p190RhoGEF) (Rho guanine nucleotide exchange factor)
Gene: ARHGEF28

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37689310
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 1705
+	Hs
		921641 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		ARG28_HUMAN (1-1705): 0: 1234: 100.00
+	Hs
		1231083 POC1B_HUMAN (517-604): 3.8e-14: 77: 18.18		ARG28_HUMAN (1-1705): 0: 1234: 100.00
+	Hs
		1016918 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		AKP13_HUMAN (1-814): 3.86e-122: 429: 17.82
+	Hs
		1146697 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ARHG2_HUMAN (615-1525): 1.22e-103: 358: 35.81
+	Hs
		1146905 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ITSN2_HUMAN (826-1215): 3.82e-85: 311: 21.78
+	Hs
		1146952 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		PKHG1_HUMAN (741-1451): 2.23e-76: 282: 13.35
+	Hs
		1146751 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ARHGH_HUMAN (391-1384): 1.6e-72: 271: 15.35
+	Hs
		920994 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		ARHGI_HUMAN (366-1514): 8.24e-108: 378: 34.48
+	Mm
		93406 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		AKP13_MOUSE (394-1532): 1.12e-117: 416: 31.35
+	Hs
		1288351 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		ITSN2_HUMAN (826-1215): 3.82e-85: 311: 21.78
+	Hs
		61736 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		A6H8W8_HUMAN (826-1215): 9.32e-85: 310: 21.78
+	Hs
		921674 GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62		ARHG2_HUMAN (615-1525): 1.22e-103: 358: 35.81
+	Mm
		1141825 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		ARHG2_MOUSE (615-1525): 6.37e-103: 356: 34.81
+	Hs
		903416 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		ARHG2_HUMAN (615-1525): 1.22e-103: 358: 35.81
+	Mm
		70591 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		B2RR82_MOUSE (826-1215): 1.39e-85: 313: 21.78
+	Hs
		1202775 WDR5B_HUMAN (165-393): 1.21e-20: 95.1: 11.72		ARHG1_HUMAN (499-1351): 7.21e-81: 289: 18.20
+	Hs
		224710 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		KALRN_HUMAN (792-1607): 6.34e-51: 201: 12.98
+	Hs
		1137768 POC1B_HUMAN (517-604): 3.8e-14: 77: 18.18		OBSCN_HUMAN (603-1420): 2.49e-75: 281: 11.80
+	Mm
		654987 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		VAV_MOUSE (792-1194): 9.95e-43: 171: 19.66