HitPredict

Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: ASPP1 (Q96KQ4)
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Gene: PPP1R13B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28594407, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 607 Hs			1 1090
+	Hs
		1146662 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		IASPP_HUMAN (336-1089): 6.59e-57: 214: 22.46
+	Hs
		1146832 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		TNKS2_HUMAN (747-1085): 1.49e-51: 200: 13.01
+	Hs
		1146620 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ANR44_HUMAN (750-1058): 2.63e-46: 183: 14.11
+	Hs
		1146951 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		ANR50_HUMAN (872-1088): 2.19e-39: 161: 17.70
+	Hs
		1146762 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		PP16B_HUMAN (907-999): 1.89e-17: 89.1: 38.71
+	Hs
		161384 A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00		MYPT1_HUMAN (821-1021): 1.28e-14: 81.1: 24.27
+	Hs
		1256324 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97
+	Hs
		921017 GBB1_HUMAN (165-516): 5.41e-43: 159: 17.18		DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97
+	Hs
		1256407 GBB4_HUMAN (165-516): 4.49e-42: 156: 16.07		DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97
+	Hs
		1288300 SNR40_HUMAN (175-514): 5.61e-65: 218: 16.48		TNKS2_HUMAN (747-1085): 1.49e-51: 200: 13.01
+	Hs
		166894 LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98		ANR28_HUMAN (709-1086): 2.22e-47: 186: 12.88
+	Hs
		903382 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		DOT1L_HUMAN (94-844): 1.19e-72: 266: 16.97
+	Mm
		71296 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		ANR44_MOUSE (750-1052): 9.2e-46: 181: 13.65
+	Hs
		1264909 STRN4_HUMAN (438-605): 8.01e-24: 108: 12.89		CTTB2_HUMAN (541-1085): 6.61e-36: 150: 13.35
+	Hs
		903444 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		EHMT2_HUMAN (643-994): 1.76e-30: 132: 12.47
+	Mm
		1207785 A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25		MYPT1_MOUSE (821-1021): 3.58e-14: 79.5: 22.82
+	Hs
		903354 WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45		ANKH1_HUMAN (834-987): 1.75e-19: 97.1: 19.28
+	Hs
		161406 POC1A_HUMAN (188-352): 4.31e-16: 82.8: 13.98		MYPT1_HUMAN (821-1021): 1.28e-14: 81.1: 24.27