Interactor 1: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Interactor 2: ATG5 (Q9H1Y0)
Autophagy protein 5 (APG5-like) (Apoptosis-specific protein)
Gene: ATG5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.769

The method score is based on:

Property Details
Experiments 23202584, 25484072, 28253979, 26975471, 26083323, 24777476, 22082872, 29634390, 33024031, 32129924, 33961781, 36576150, 20562859, 22342342, 28994404, 30196744, 29360461, 28594407, 22847423, 31636955 and 6 others

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Identification Methods x-ray crystallography, two hybrid, pull down, affinity chromatography technology, proximity labelling technology, protein complementation assay, biochemical, molecular sieving, ion exchange chromatography, anti tag coimmunoprecipitation
Interaction Type association, direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000045 - autophagosome assembly
GO:0005776 - autophagosome
GO:0005829 - cytosol
GO:0005930 - axoneme
GO:0016236 - macroautophagy
and 3 others

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Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 607
Hs

1 275
+ Hs
+ Dm
+ Ce
+ Mm
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024