HitPredict

Interactor 1: NR3L1 (Q68D85)
Natural cytotoxicity triggering receptor 3 ligand 1 (B7 homolog 6) (B7-H6)
Gene: NCR3LG1

Interactor 2: TMPS4 (Q9NRS4)
Transmembrane protease serine 4 (EC 3.4.21.-) (Channel-activating protease 2) (CAPH2) (Membrane-type serine protease 2) (MT-SP2) [Cleaved into: Transmembrane protease serine 4 catalytic chain]
Gene: TMPRSS4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34709727
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1-set~Trypsin
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 454 Hs			1 437
+	Hs
		1147802 NR3L1_HUMAN (1-454): 1.09e-146: 427: 100.00		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		1182913 BT2A1_HUMAN (19-324): 1.78e-34: 137: 14.79		TMPS4_HUMAN (1-437): 8.94e-167: 477: 100.00
+	Hs
		545175 PVR_HUMAN (18-261): 5.52e-32: 128: 23.29		TMPS4_HUMAN (1-437): 8.94e-167: 477: 100.00
+	Hs
		382540 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		TMPS4_HUMAN (1-437): 8.94e-167: 477: 100.00
+	Hs
		355061 DQB1_HUMAN (121-243): 1.6e-22: 98.4: 21.14		TMPS4_HUMAN (1-437): 8.94e-167: 477: 100.00
+	Hs
		1269118 NECT2_HUMAN (21-261): 2.04e-31: 128: 20.23		TMPSD_HUMAN (44-434): 8.88e-118: 357: 33.33
+	Hs
		1045062 CD166_HUMAN (8-259): 1.78e-30: 125: 15.89		TMPSD_HUMAN (44-434): 8.88e-118: 357: 33.33
+	Hs
		382369 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		TMPS3_HUMAN (62-437): 1.1e-118: 355: 34.18
+	Hs
		1269142 NECT2_HUMAN (21-261): 2.04e-31: 128: 20.23		ST14_HUMAN (54-434): 9.27e-109: 342: 25.65
+	Hs
		177812 PVR_HUMAN (18-261): 5.52e-32: 128: 23.29		TMPS2_HUMAN (44-436): 2.07e-111: 338: 34.41
+	Hs
		177778 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		TMPS2_HUMAN (44-436): 2.07e-111: 338: 34.41
+	Hs
		1141032 CD276_HUMAN (1-396): 1.95e-39: 150: 18.01		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		1355887 BTNL2_HUMAN (32-275): 1.61e-22: 101: 16.67		ST14_HUMAN (54-434): 9.27e-109: 342: 25.65
+	Hs
		1198117 NECT2_HUMAN (21-261): 2.04e-31: 128: 20.23		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		545133 PVR_HUMAN (18-261): 5.52e-32: 128: 23.29		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		409542 NECT2_HUMAN (21-261): 2.04e-31: 128: 20.23		HEPS_HUMAN (95-434): 4.41e-97: 299: 33.43
+	Hs
		382468 HLAA_HUMAN (113-296): 5.54e-30: 121: 20.86		TM11B_HUMAN (187-434): 1.43e-99: 305: 36.80
+	Hs
		341323 BTNL2_HUMAN (32-275): 1.61e-22: 101: 16.67		FA10_HUMAN (77-434): 1.55e-101: 313: 26.79